Therapeutic Drug Monitoring Is a Feasible Tool to Personalize Drug Administration in Neonates Using New Techniques: An Overview on the Pharmacokinetics and Pharmacodynamics in Neonatal Age.

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作者： Domenico Umberto,De Rose ^[1] ; Sara,Cairoli ^[2] ; Marco,Dionisi ^[2] ; Alessandra,Santisi ^[1] ; Luca,Massenzi ^[3] ; Bianca Maria,Goffredo ^[2] ; Carlo,Dionisi-Vici ^[2] ; Andrea,Dotta ^[1] ; Cinzia,Auriti ^[1]

作者单位： Neonatal Intensive Care Unit, Department of Medical and Surgical Neonatology, "Bambino Gesù" Children's Hospital IRCCS, 00165 Rome, Italy. ^[1] Laboratory of Metabolic Biochemistry Unit, Department of Specialist Pediatrics, "Bambino Gesù" Children's Hospital IRCCS, 00165 Rome, Italy. ^[2] Neonatal Intensive Care Unit and Neonatal Pathology, Fatebenefratelli Hospital, 00186 Rome, Italy. ^[3]

关键词 drugs infants neonates newborns personalized medicine pharmacodynamics pharmacokinetics therapeutic drug monitoring

主题词抗感染药(Anti-Infective Agents);抗惊厥药(Anticonvulsants);药物监测(Drug Monitoring);人类(Humans);婴儿, 新生(Infant, Newborn);代谢清除率(Metabolic Clearance Rate)

DOI 10.3390/ijms21165898

PMID 32824472

发布时间 2024-03-29

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