A new coumarin compound DCH combats methicillin-resistant <i>Staphylococcus aureus</i> biofilm by targeting arginine repressor.

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第一作者： Di,Qu

第一单位： Department of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi'an 710032, China.

作者： Di,Qu ^[1] ; Zheng,Hou ^[1] ; Jing,Li ^[2] ; Liyang,Luo ^[1] ; Shan,Su ^[1] ; Zichen,Ye ^[3] ; Yinlan,Bai ^[4] ; Xinlei,Zhang ^[5] ; Guanghui,Chen ^[1] ; Zhoupeng,Li ^[1] ; Yikun,Wang ^[1] ; Xiaoyan,Xue ^[1] ; Xiaoxing,Luo ^[1] ; Mingkai,Li ^[1]

作者单位： Department of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi'an 710032, China. ^[1] Key Laboratory for Surface Engineering and Remanufacturing in Shaanxi province, School of Chemical Engineering, Xi'an University, Xi'an 710065, China. ^[2] Department of Pharmacogenomics, School of Pharmacy, The Fourth Military Medical University, Xi'an 710032, China. ^[3] Department of Microbiology, School of Basic Medicine, The Fourth Military Medical University, Xi'an 710032, China. ^[4] Department of Medical Chemistry, School of Pharmacy, The Fourth Military Medical University, Xi'an 710032, China. ^[5] Precision Pharmacy and Drug Development Center, The Fourth Military Medical University, Xi'an 710032, China. ^[6]

主题词抗菌药(Anti-Bacterial Agents);精氨酸(Arginine);生物膜(Biofilms);香豆素类(Coumarins);耐甲氧西林金黄色葡萄球菌(Methicillin-Resistant Staphylococcus aureus)

DOI 10.1126/sciadv.aay9597

PMID 32832655

发布时间 2022-04-11

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Science advances

2020年6卷30期

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A new coumarin compound DCH combats methicillin-resistant <i>Staphylococcus aureus</i> biofilm by targeting arginine repressor.

Science advances

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A new coumarin compound DCH combats methicillin-resistant <i>Staphylococcus aureus</i> biofilm by targeting arginine repressor.

Science advances

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