Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate.
作者:
Akhilesh,Pandey [1]
;
Eric W,Stawiski [2]
;
Steffen,Durinck [3]
;
Harsha,Gowda [4]
;
Leonard D,Goldstein [5]
;
Mustafa A,Barbhuiya [6]
;
Markus S,Schröder [7]
;
Sreelakshmi K,Sreenivasamurthy [8]
;
Sun-Whe,Kim [9]
;
Sameer,Phalke [10]
;
Kushal,Suryamohan [7]
;
Kayla,Lee [8]
;
Papia,Chakraborty [9]
;
Vasumathi,Kode [11]
;
Xiaoshan,Shi [8]
;
Aditi,Chatterjee [12]
;
Keshava,Datta [9]
;
Aafaque A,Khan [13]
;
Tejaswini,Subbannayya [14]
;
Jing,Wang [15]
;
Subhra,Chaudhuri [15]
;
Sanjiv,Gupta [15]
;
Braj Raj,Shrivastav [15]
;
Bijay S,Jaiswal [15]
;
Satish S,Poojary [9]
;
Shushruta,Bhunia [9]
;
Patricia,Garcia [9]
;
Carolina,Bizama [9]
;
Lorena,Rosa [15]
;
Wooil,Kwon [8]
;
Hongbeom,Kim [16]
;
Youngmin,Han [17]
;
Thakur Deen,Yadav [8]
;
Vedam L,Ramprasad [18]
;
Amitabha,Chaudhuri [18]
;
Zora,Modrusan [19]
;
Juan Carlos,Roa [19]
;
Pramod Kumar,Tiwari [20]
;
Jin-Young,Jang [13]
;
Somasekar,Seshagiri [13]
作者单位:
Institute of Bioinformatics, Bangalore, Karnataka, 560066, India. pandey.akhilesh@mayo.edu.
[1]
Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, 576104, India. pandey.akhilesh@mayo.edu.
[2]
Center for Individualized Medicine and Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA. pandey.akhilesh@mayo.edu.
[3]
Bioinformatics and Computational Biology Department, Genentech Inc, South San Francisco, CA, 94080, USA. eric.s@medgenome.com.
[4]
Molecular Biology Department, Genentech Inc., South San Francisco, CA, 94080, USA. eric.s@medgenome.com.
[5]
Research and Development Department, MedGenome Inc, Foster City, CA, 94404, USA. eric.s@medgenome.com.
[6]
Bioinformatics and Computational Biology Department, Genentech Inc, South San Francisco, CA, 94080, USA.
[7]
Molecular Biology Department, Genentech Inc., South San Francisco, CA, 94080, USA.
[8]
Institute of Bioinformatics, Bangalore, Karnataka, 560066, India.
[9]
QIMR Berghofer Medical Research Institute, Brisbane, QLD, 4006, Australia.
[10]
Department of Pathology and Laboratory Medicine, Pennsylvania State University College of Medicine, Hershey, PA, 17033, USA.
[11]
SciGenom Labs, Cochin, Kerala, 682037, India.
[12]
Department of Surgery, Division of Hepatobiliary and Pancreatic Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, 08826, South Korea.
[13]
Research and Development Department, MedGenome Labs Pvt. Ltd., Bangalore, Karnataka, 560099, India.
[14]
Research and Development Department, MedGenome Inc, Foster City, CA, 94404, USA.
[15]
Department of Pathology, Cancer Hospital and Research Institute, Gwalior, Madhya Pradesh, 474009, India.
[16]
Department of Surgical Oncology, Cancer Hospital and Research Institute, Gwalior, Madhya Pradesh, 474009, India.
[17]
Jiwaji University, Gwalior, Madhya Pradesh, 474011, India.
[18]
Department of Pathology, Millennium Institute on Immunology and Immunotherapy, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
[19]
Applied Molecular and Cellular Biology PhD Program Universidad De la Frontera, Temuco, Chile.
[20]
Department of Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.
[21]
Department of Surgery, Division of Hepatobiliary and Pancreatic Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, 08826, South Korea. jangjy4@snu.ac.kr.
[22]
Molecular Biology Department, Genentech Inc., South San Francisco, CA, 94080, USA. sekar@sgrf.org.
[23]
SciGenom Research Foundation, 3rd Floor, Narayana Nethralaya Building, Narayana Health City, #258/A, Bommasandra, Hosur Road, Bangalore, Karnataka, 560099, India. sekar@sgrf.org.
[24]
主题词
癌症疫苗(Cancer Vaccines);智利(Chile);DNA结合蛋白质类(DNA-Binding Proteins);移码突变(Frameshift Mutation);胆囊肿瘤(Gallbladder Neoplasms);基因表达谱(Gene Expression Profiling);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);疾病遗传易感性(Genetic Predisposition to Disease);基因组学(Genomics);人类(Humans);印度(India);NF-E2相关因子2(NF-E2-Related Factor 2);原癌基因蛋白质c-ets(Proto-Oncogene Proteins c-ets);韩国(Republic of Korea);转录因子(Transcription Factors);β连环素(beta Catenin)
DOI
10.1038/s41467-020-17880-4
PMID
32839463
发布时间
2024-03-29
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Nature communications
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