Mapping Lipogenic Flux: A Gold LDI-MS Approach for Imaging Neutral Lipid Kinetics.

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作者： Daniel P,Downes ^[1] ; Wendy,Zhong ^[2] ; Ji,Zhang ^[3] ; Bingming,Chen ^[4] ; Santhosh,Satapati ^[3] ; Daniel,Metzger ^[3] ; Guillermo,Godinez ^[3] ; Julie,Lao ^[3] ; Payal R,Sheth ^[1] ; David G,McLaren ^[1] ; Saswata,Talukdar ^[3] ; Stephen F,Previs ^[1]

作者单位： Merck & Co., Inc, 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States. ^[1] Merck & Co., Inc, 90 East Scott Avenue, Rahway, New Jersey 07065, United States. ^[2] Merck & Co., Inc, 213 East Grand Avenue, South San Francisco, California 94080, United States. ^[3] Merck & Co., Inc, 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States. ^[4]

关键词 imaging mass spectrometry lipid metabolism stable isotope tracer

主题词动物(Animals);金(Gold);动力学(Kinetics);脂类(Lipids);男(雄)性(Male);质谱分析法(Mass Spectrometry);小鼠, 近交C57BL(Mice, Inbred C57BL)

DOI 10.1021/jasms.0c00199

PMID 32840373

发布时间 2021-10-14

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