Fixed-dose combination of indacaterol/glycopyrronium/mometasone furoate once-daily versus salmeterol/fluticasone twice-daily plus tiotropium once-daily in patients with uncontrolled asthma: A randomised, Phase IIIb, non-inferiority study (ARGON).

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作者： Christian,Gessner ^[1] ; Oliver,Kornmann ^[2] ; Jorge,Maspero ^[3] ; Richard,van Zyl-Smit ^[4] ; Matthias,Krüll ^[5] ; Anna,Salina ^[6] ; Pritam,Gupta ^[7] ; Sebastien,Bostel ^[6] ; Sebastian,Fucile ^[8] ; Lorena Garcia,Conde ^[6] ; Pascal,Pfister ^[6]

作者单位： Universitätsklinikum Leipzig, Germany POIS Leipzig GbR, Leipzig, Germany. Electronic address: studien@pois-le.de. ^[1] IKF Pneumologie Frankfurt, Clinical Research Centre Respiratory Diseases, Frankfurt, Germany. ^[2] Allergy and Respiratory Research Unit, Fundación CIDEA, Buenos Aires, Argentina. ^[3] Division of Pulmonology and UCT Lung Institute, University of Cape Town, Cape Town, South Africa. ^[4] Institut für Allergie- und Asthmaforschung Berlin, IAAB, Germany. ^[5] Novartis Pharma AG, Basel, Switzerland. ^[6] Novartis Healthcare Pvt. Ltd, Hyderabad, India. ^[7] Novartis Pharmaceuticals Corporation, East Hanover, NJ, United States. ^[8]

关键词 AQLQ Indacaterol/glycopyrronium/mometasone Lung function Non-inferiority Salmeterol/fluticasone Tiotropium

主题词投药, 吸入(Administration, Inhalation);成年人(Adult);老年人(Aged);剂量效应关系, 药物(Dose-Response Relationship, Drug);复方合剂(Drug Combinations);药物疗法, 联合(Drug Therapy, Combination);女(雌)性(Female);格隆溴铵(Glycopyrrolate);人类(Humans);茚满类(Indans);男(雄)性(Male);中年人(Middle Aged);生活质量(Quality of Life);喹诺酮类(Quinolones);治疗结果(Treatment Outcome)

DOI 10.1016/j.rmed.2020.106021

PMID 32843164

发布时间 2021-06-07

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Respiratory medicine

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Fixed-dose combination of indacaterol/glycopyrronium/mometasone furoate once-daily versus salmeterol/fluticasone twice-daily plus tiotropium once-daily in patients with uncontrolled asthma: A randomised, Phase IIIb, non-inferiority study (ARGON).

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Fixed-dose combination of indacaterol/glycopyrronium/mometasone furoate once-daily versus salmeterol/fluticasone twice-daily plus tiotropium once-daily in patients with uncontrolled asthma: A randomised, Phase IIIb, non-inferiority study (ARGON).

Respiratory medicine

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Respiratory medicine

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