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A mutation in POLR3E impairs antiviral immune response and RNA polymerase III.

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第一作者： Aravind,Ramanathan

第一单位： Microbiology and Molecular Genetics, Institute of Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, 9112102 Jerusalem, Israel.

作者： Aravind,Ramanathan ^[1] ; Michael,Weintraub ^[2] ; Natalie,Orlovetskie ^[1] ; Raphael,Serruya ^[1] ; Dhivakar,Mani ^[1] ; Orly,Marcu ^[1] ; Polina,Stepensky ^[3] ; Yiska,Weisblum ^[4] ; Esther,Djian ^[4] ; Avraham,Shaag ^[5] ; Shoshana,Revel-Vilk ^[6] ; Iris,Fried ^[7] ; Moshe,Kotler ^[4] ; Alex,Rouvinski ^[1] ; Dana,Wolf ^[5] ; Orly,Elpeleg ^[8] ; Nayef,Jarrous ^[9]

作者单位： Microbiology and Molecular Genetics, Institute of Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, 9112102 Jerusalem, Israel. ^[1] Brain Injury Clinic, Alyn Rehabilitation Hospital for Children, 91090 Jerusalem, Israel; michaelweintraub1958@gmail.com elpeleg@hadassah.org.il nayefj@ekmd.huji.ac.il. ^[2] Pediatric Hematology-Oncology, Hadassah-Hebrew University Medical Center, 9112102 Jerusalem, Israel. ^[3] Department of Pathology and Immunology, The Lautenberg Center for Immunology and Cancer Research, The Hebrew University-Hadassah Medical School, 9112102 Jerusalem, Israel. ^[4] Microbiology and Infectious Diseases, Hadassah-Hebrew University Medical Center, 9112102 Jerusalem, Israel. ^[5] Pediatric Hematology/Oncology Unit, Shaare Zedek Medical Center, 9103102 Jerusalem, Israel.;The Hebrew University Hadassah Medical School, 9112102 Jerusalem, Israel. ^[6] Pediatric Hematology/Oncology Unit, Shaare Zedek Medical Center, 9103102 Jerusalem, Israel. ^[7] Department of Genetics, Hadassah-Hebrew University Medical Center, 9112102 Jerusalem, Israel michaelweintraub1958@gmail.com elpeleg@hadassah.org.il nayefj@ekmd.huji.ac.il. ^[8] Microbiology and Molecular Genetics, Institute of Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, 9112102 Jerusalem, Israel; michaelweintraub1958@gmail.com elpeleg@hadassah.org.il nayefj@ekmd.huji.ac.il. ^[9]

关键词 POLR3E RNA polymerase III cytomegalovirus innate immunity transcription