Multidisciplinary Preclinical Investigations on Three Oxamniquine Analogues as New Drug Candidates for Schistosomiasis*.

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作者： Valentin,Buchter ^[1] ; Yih Ching,Ong ^[2] ; François,Mouvet ^[3] ; Abdallah,Ladaycia ^[4] ; Elise,Lepeltier ^[5] ; Ursula,Rothlisberger ^[5] ; Jennifer,Keiser ^[4] ; Gilles,Gasser ^[1]

作者单位： Swiss Tropical and Public Health Institute, Socinstrasse 57, P.O. box, 4002, Basel, Switzerland. ^[1] University of Basel, Petersplatz 1, P.O. Box, 4001, Basel, Switzerland. ^[2] Chimie ParisTech, PSL University, CNRS, Institute of Chemistry for Life and Health Sciences, Laboratory of Inorganic Chemical Biology, 75005, Paris, France. ^[3] Laboratory of Computational Chemistry and Biochemistry, EPFL, 1015, Lausanne, Switzerland. ^[4] MINT, UNIV Angers, INSERM 1066, CNRS 6021, Université Bretagne Loire, 4 rue Larrey, 49933, Angers Cedex 9, France. ^[5]

关键词 bioinorganic chemistry drug delivery drug discovery medicinal chemistry molecular dynamics schistosomiasis

主题词动物(Animals);人类(Humans);奥沙尼喹(Oxamniquine);药用制剂(Pharmaceutical Preparations);曼森血吸虫(Schistosoma mansoni);血吸虫病(Schistosomiasis);曼森血吸虫病(Schistosomiasis mansoni)

DOI 10.1002/chem.202002856

PMID 32852116

发布时间 2021-02-16

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