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Circulating Tumor DNA Genomics Reveal Potential Mechanisms of Resistance to BRAF-Targeted Therapies in Patients with <i>BRAF</i>-Mutant Metastatic Non-Small Cell Lung Cancer.

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作者单位: Univ Lyon, Claude Bernard Lyon 1 University, INSERM 1052, CNRS 5286, Centre Léon Bérard, Cancer Research Center of Lyon, Lyon, France. david.planchard@gustaveroussy.fr sandra.ortiz-cuaran@lyon.unicancer.fr pierre.saintigny@lyon.unicancer.fr. [1] Department of Cancer Medicine, Gustave Roussy Cancer Campus, Villejuif, France. [2] Department of Medical Oncology, Hospital Clinic, Laboratory of Translational Genomics and Targeted Therapeutics in Solid Tumors, IDIBAPS, Barcelona, Spain. [3] Univ Lyon, Claude Bernard Lyon 1 University, INSERM 1052, CNRS 5286, Centre Léon Bérard, Cancer Research Center of Lyon, Lyon, France. [4] Department of Medical Oncology, Centre Léon Bérard &amp; Université Claude Bernard Lyon I/Université de Lyon, Lyon, France. [5] Department of Respiratory Disease, Larrey Hospital, University Hospital of Toulouse, Paul Sabatier University, Toulouse, France. [6] Translational Research Laboratory, Gustave Roussy Cancer Campus, Villejuif, France. [7] Institut Claudius Regaud, Toulouse, France. [8] Hospices Civils de Lyon, Lyon, France. [9] University Hospital of Besancon, Besançon, France. [10] Department of Early Drug Development, Gustave Roussy Cancer Campus, Villejuif, France. [11] University Hospital of Saint-Etienne, Saint-Etienne, France. [12] Centre Hospitalier Argenteuil, Argenteuil, France. [13] Centre François Baclesse, Caen, France. [14] Hôpital René Huguenin, Saint-Cloud, France. [15] Centre Hospitalier Intercommunal de Créteil, Creteil, France. [16] APHP-Hôpital Ambroise Paré and Université Paris Saclay, Paris, France. [17] Department of Radiology, Gustave Roussy Cancer Campus, Villejuif, France. [18] Unicancer, Paris, France. [19] Institut National du Cancer, Boulogne-Billancourt, France. [20] Inivata Ltd, Cambridge, United Kingdom. [21] Université Paris-Saclay, Gustave Roussy Cancer Campus, Inserm, Biomarqueurs Prédictifs et Nouvelles Stratégies Thérapeutiques en Oncologie, Villejuif, France. [22] Department of Clinical Research, Centre Léon Bérard, Lyon, France. [23] Centre de Biochimie Structurale (CBS), INSERM, CNRS, Université de Montpellier, Montpellier, France. [24] Department of Cancer Medicine, Gustave Roussy Cancer Campus, Villejuif, France. david.planchard@gustaveroussy.fr sandra.ortiz-cuaran@lyon.unicancer.fr pierre.saintigny@lyon.unicancer.fr. [25]
DOI 10.1158/1078-0432.CCR-20-1037
PMID 32859654
发布时间 2021-12-14
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Clinical cancer research : an official journal of the American Association for Cancer Research

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