Tumor copy number instability is a significant predictor for late recurrence after radical surgery of pancreatic ductal adenocarcinoma.

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作者： Chenlei,Wen ^[1] ; XiaXing,Deng ^[2] ; Dandan,Ren ^[1] ; Xue,Song ^[2] ; Hao,Chen ^[3] ; Jiancheng,Wang ^[3] ; Jiabin,Jin ^[1] ; Dongfeng,Cheng ^[2] ; Zhiwei,Xu ^[1] ; Jun,Zhang ^[2] ; Junjie,Xie ^[1] ; Wenjing,Qi ^[2] ; Jiangning,Gu ^[1] ; Chenghong,Peng ^[2] ; Dan,Chen ^[1] ; Shi,Chen ^[2] ; Baiyong,Shen ^[1] ; Qian,Zhan ^[2]

作者单位： Department of General Surgery, Pancreatic Disease Center, Research Institute of Pancreatic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ^[1] State Key Laboratory of Oncogenes and Related Genes, Institute of Translational Medicine, Shanghai Jiao Tong University, Shanghai, China. ^[2] Genecast Biotechnology Co., Ltd, Wuxi, China. ^[3] Department of Pathology, The First affiliated Hospital of Dalian Medical University, Dalian, China. ^[4] Department of Hepatobiliary Surgery, The First affiliated Hospital of Dalian Medical University, Dalian, China. ^[5] Department of Hepato-Biliary-Pancreatic Surgery, Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fujian Medical University, Fuzhou, China. ^[6]

关键词 copy number instability late recurrence pancreatic ductal adenocarcinoma predictive marker prognosis

主题词成年人(Adult);老年人(Aged);活组织检查(Biopsy);癌, 胰腺管(Carcinoma, Pancreatic Ductal);DNA拷贝数变异(DNA Copy Number Variations);女(雌)性(Female);人类(Humans);免疫组织化学(Immunohistochemistry);男(雄)性(Male);中年人(Middle Aged);突变(Mutation);肿瘤复发, 局部(Neoplasm Recurrence, Local);肿瘤分期(Neoplasm Staging);胰腺切除术(Pancreatectomy);预后(Prognosis);ROC曲线(ROC Curve);存活率分析(Survival Analysis);肿瘤负荷(Tumor Burden)

DOI 10.1002/cam4.3425

PMID 32862515

发布时间 2021-05-19

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Cancer medicine

2020年9卷20期

7626-7636页

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Tumor copy number instability is a significant predictor for late recurrence after radical surgery of pancreatic ductal adenocarcinoma.

Cancer medicine

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Tumor copy number instability is a significant predictor for late recurrence after radical surgery of pancreatic ductal adenocarcinoma.

Cancer medicine

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Cancer medicine

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