首页> Journal of proteome research> Immunoaffinity Targeted Mass Spectrometry Analysis of Human Plasma Samples Reveals an Imbalance of Active and Inactive CXCL10 in Primary Sjögren's Syndrome Disease Patients.

Immunoaffinity Targeted Mass Spectrometry Analysis of Human Plasma Samples Reveals an Imbalance of Active and Inactive CXCL10 in Primary Sjögren's Syndrome Disease Patients.

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第一作者： Alexander,Schmidt

第一单位： Biozentrum, University of Basel, Klingelbergstrasse 50/70, CH-4056 Basel, Switzerland.

作者： Alexander,Schmidt ^[1] ; Hervé,Farine ^[2] ; Marcel P,Keller ^[2] ; Agata,Sebastian ^[3] ; Lukasz,Kozera ^[4] ; Richard W D,Welford ^[2] ; Daniel S,Strasser ^[2]

作者单位： Biozentrum, University of Basel, Klingelbergstrasse 50/70, CH-4056 Basel, Switzerland. ^[1] Idorsia Pharmaceuticals, Ltd, Hegenheimermattweg 91, CH-4123 Allschwil, Switzerland. ^[2] Department of Rheumatology and Internal Medicine, Wroclaw Medical University, Borowska 210, 50-556 Wroclaw, Poland. ^[3] Lukasiewicz Research Network - PORT Polish Center for Technology Development, National Biobanking Node, Stablowicka 147, 50-066 Wroclaw, Poland. ^[4]

关键词 CXCL10 DPP4 N-terminal degradation parallel reaction monitoring primary Sj?gren’s Syndrome proteoform quantification stable isotope dilution targeted mass spectrometry

医学主题词趋化因子CXCL10(Chemokine CXCL10);酶联免疫吸附测定(Enzyme-Linked Immunosorbent Assay);人类(Humans);红斑狼疮, 系统性(Lupus Erythematosus, Systemic);质谱分析法(Mass Spectrometry);干燥综合征(Sjogren's Syndrome)

DOI 10.1021/acs.jproteome.0c00494

PMID 32870689

发布时间 2022-05-31

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