Proteomics and Metabolomics Approaches towards a Functional Insight onto AUTISM Spectrum Disorders: Phenotype Stratification and Biomarker Discovery.

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第一作者： Maria Vittoria,Ristori

第一单位： Department of Laboratories, Unit of Parasitology and Area of Genetics and Rare Diseases, Unit of Human Microbiome, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.

作者： Maria Vittoria,Ristori ^[1] ; Stefano Levi,Mortera ^[2] ; Valeria,Marzano ^[2] ; Silvia,Guerrera ^[3] ; Pamela,Vernocchi ^[2] ; Gianluca,Ianiro ^[4] ; Simone,Gardini ^[5] ; Giuliano,Torre ^[6] ; Giovanni,Valeri ^[3] ; Stefano,Vicari ^[7] ; Antonio,Gasbarrini ^[8] ; Lorenza,Putignani ^[1]

作者单位： Department of Laboratories, Unit of Parasitology and Area of Genetics and Rare Diseases, Unit of Human Microbiome, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy. ^[1] Area of Genetics and Rare Diseases, Unit of Human Microbiome, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy. ^[2] Department of Neuroscience, Unit of Head Child & Adolescent Psychiatry, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy. ^[3] Dipartimento di Gastroenterologia, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli 8, 00168 Rome, Italy. ^[4] GENOMEUP S.R.L, Viale Pasteur 8, 00144 Rome, Italy. ^[5] Department of Specialist Pediatricians and Liver-Kidney Transplantation, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy. ^[6] Department of Neuroscience, Unit of Head Child & Adolescent Psychiatry, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.;Department of Life Sciences and Public Health, Catholic University, 00153 Rome, Italy. ^[7] Istituto di Patologia Speciale Medica, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.;UOC Medicina Interna e Gastroenterologia, Area Gastroenterologia ed Oncologia Medica, Dipartimento di Scienze Gastroenterologiche, Endocrino-Metaboliche e Nefro-Urologiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy. ^[8]

关键词 autism spectrum disorders (ASDs)clinical decision support systems (CDSSs)disease biomarkers interactomics metabolomics proteomics

主题词人类(Humans);代谢组(Metabolome);表型(Phenotype);蛋白质组(Proteome)

DOI 10.3390/ijms21176274

PMID 32872562

发布时间 2021-02-17

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