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B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models.

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第一作者: Deli,Huang
第一单位: Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037.
作者单位: Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037. [1] Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA 92037.;Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037. [2] Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA 92037. [3] Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037.;Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037.;International AIDS Vaccine Initiative (IAVI) Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery, The Scripps Research Institute, La Jolla, CA 92037. [4] Vaccine and Infectious Disease Division, Statistical Center for HIV/AIDS Research and Prevention, Fred Hutchinson Cancer Research Center, Seattle, WA 98109. [5] Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037.;Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037.;International AIDS Vaccine Initiative (IAVI) Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery, The Scripps Research Institute, La Jolla, CA 92037.;Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139. [6] Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037; nemazee@scripps.edu shane@lji.org. [7] Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA 92037; nemazee@scripps.edu shane@lji.org.;Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037.;Department of Medicine, Division of Infectious Diseases and Global Public Health, University of California San Diego, La Jolla, CA 92037. [8]
DOI 10.1073/pnas.2004489117
PMID 32873644
发布时间 2024-10-18
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Proceedings of the National Academy of Sciences of the United States of America

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