换一批
换一批Discovery of Bispecific Antagonists of Retinol Binding Protein 4 That Stabilize Transthyretin Tetramers: Scaffolding Hopping, Optimization, and Preclinical Pharmacological Evaluation as a Potential Therapy for Two Common Age-Related Comorbidities.
作者：
主题词
动物(Animals);生物聚合物(Biopolymers);结晶学, X线(Crystallography, X-Ray);药物设计(Drug Design);药物评价, 临床前(Drug Evaluation, Preclinical);地图样萎缩(Geographic Atrophy);人类(Humans);黄斑变性(Macular Degeneration);小鼠(Mice);分子结构(Molecular Structure);前白蛋白(Prealbumin);视黄醇结合蛋白质类, 血浆(Retinol-Binding Proteins, Plasma)
DOI
10.1021/acs.jmedchem.0c00996
PMID
32878437
发布时间
2022-10-20
- 浏览0
Journal of medicinal chemistry
11054-11084页
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