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Genome-Wide Association Study of Susceptibility Loci for TCF3-PBX1 Acute Lymphoblastic Leukemia in Children.

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第一作者： Shawn H R,Lee

第一单位： Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.;Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore.;Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

作者： Shawn H R,Lee ^[1] ; Maoxiang,Qian ^[2] ; Wentao,Yang ^[3] ; Jonathan D,Diedrich ^[3] ; Elizabeth,Raetz ^[4] ; Wenjian,Yang ^[3] ; Qian,Dong ^[3] ; Meenakshi,Devidas ^[5] ; Deqing,Pei ^[6] ; Allen,Yeoh ^[7] ; Cheng,Cheng ^[6] ; Ching-Hon,Pui ^[8] ; William E,Evans ^[3] ; Charles G,Mullighan ^[9] ; Stephen P,Hunger ^[10] ; Daniel,Savic ^[3] ; Mary V,Relling ^[3] ; Mignon L,Loh ^[11] ; Jun J,Yang ^[3]

作者单位： Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.;Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore.;Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. ^[1] Institute of Pediatrics and Department of Hematology and Oncology, Children's Hospital of Fudan University, Shanghai Key Laboratory of Medical Epigenetics, Institutes of Biomedical Sciences, Fudan University, Shanghai, China. ^[2] Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA. ^[3] Division of Pediatric Hematology and Oncology, New York University Langone Health, New York, NY, USA. ^[4] Department of Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN, USA.;Department of Biostatistics, University of Florida, Gainesville, FL, USA. ^[5] Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, USA. ^[6] Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore.;Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. ^[7] Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA. ^[8] Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA. ^[9] Department of Pediatrics and Center for Childhood Cancer Research, Children's Hospital of Philadelphia and the Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA, USA. ^[10] Department of Pediatrics, Benioff Children's Hospital and the Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA. ^[11]

医学主题词急性病(Acute Disease);疾病遗传易感性(Genetic Predisposition to Disease);全基因组关联研究(Genome-Wide Association Study);人类(Humans);癌基因蛋白质类, 融合(Oncogene Proteins, Fusion);前体细胞淋巴母细胞白血病淋巴瘤(Precursor Cell Lymphoblastic Leukemia-Lymphoma)

DOI 10.1093/jnci/djaa133

PMID 32882024

发布时间 2026-04-15

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