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首页> Environmental toxicology and pharmacology> Luteolin supplementation ameliorates cobalt-induced oxidative stress and inflammation by suppressing NF-кB/Kim-1 signaling in the heart and kidney of rats.

Luteolin supplementation ameliorates cobalt-induced oxidative stress and inflammation by suppressing NF-кB/Kim-1 signaling in the heart and kidney of rats.

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作者： Ademola Adetokunbo,Oyagbemi ^[1] ; Akinleye Stephen,Akinrinde ^[2] ; Olamide Elizabeth,Adebiyi ^[1] ; Theophilus Aghogho,Jarikre ^[3] ; Temidayo Olutayo,Omobowale ^[4] ; Olufunke Eunice,Ola-Davies ^[1] ; Adebowale Benard,Saba ^[5] ; Benjamin Obukowho,Emikpe ^[4] ; Adeolu Alex,Adedapo ^[5]

作者单位： Department of Veterinary Physiology and Biochemistry, Faculty of Veterinary Medicine, University of Ibadan, Nigeria. ^[1] Department of Veterinary Physiology and Biochemistry, Faculty of Veterinary Medicine, University of Ibadan, Nigeria. Electronic address: as.akinrinde@mail.ui.edu.ng. ^[2] Department of Veterinary Pathology, Faculty of Veterinary Medicine, University of Ibadan, Nigeria. ^[3] Department of Veterinary Medicine, Faculty of Veterinary Medicine, University of Ibadan, Nigeria. ^[4] Department of Veterinary Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Ibadan, Nigeria. ^[5]

关键词 Cardiomyopathy Cobalt Kidney injury Kidney injury molecule-1 Luteolin Nuclear factor-κappa B

主题词急性肾损伤(Acute Kidney Injury);动物(Animals);消炎药(Anti-Inflammatory Agents);细胞黏附分子(Cell Adhesion Molecules);钴(Cobalt);营养保健品(Dietary Supplements);没食子酸(Gallic Acid);肾(Kidney);木犀草素(Luteolin);男(雄)性(Male);心肌(Myocardium);NF-κB(NF-kappa B);氧化性应激(Oxidative Stress);大鼠, Wistar(Rats, Wistar);信号传导(Signal Transduction)

DOI 10.1016/j.etap.2020.103488

PMID 32898663

发布时间 2021-02-03

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Environmental toxicology and pharmacology

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