Differential regulation of rho GTPases during lung adenocarcinoma migration and invasion reveals a novel role of the tumor suppressor StarD13 in invadopodia regulation.

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第一作者： Maria,Al Haddad

第一单位： Department of Natural Sciences, School of Arts and Sciences, Lebanese American University, P.O. Box: 13-5053. Chouran, Beirut, 1102 2801, Lebanon.

作者： Maria,Al Haddad ^[1] ; Rayane,El-Rif ^[1] ; Samer,Hanna ^[2] ; Leila,Jaafar ^[1] ; Rayanne,Dennaoui ^[1] ; Sandra,Abdellatef ^[1] ; Veronika,Miskolci ^[3] ; Dianne,Cox ^[4] ; Louis,Hodgson ^[4] ; Mirvat,El-Sibai ^[5]

作者单位： Department of Natural Sciences, School of Arts and Sciences, Lebanese American University, P.O. Box: 13-5053. Chouran, Beirut, 1102 2801, Lebanon. ^[1] Department of Pediatrics HemeOnc division, Weill Cornell Medicine, Joan & Sanford I. Weill Medical College of Cornell University, New York, USA. ^[2] Department of Medical Microbiology and Immunology, University of Wisconsin - Madison, Madison, WI, 53706, USA. ^[3] Department of Anatomy and Structural Biology, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York, USA.;Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York, USA. ^[4] Department of Natural Sciences, School of Arts and Sciences, Lebanese American University, P.O. Box: 13-5053. Chouran, Beirut, 1102 2801, Lebanon. mirvat.elsibai@lau.edu.lb. ^[5]

关键词 Invadopodia Invasion Migration Rho GTPases StarD13

主题词细胞运动(Cell Movement);GTP酶激活蛋白质类(GTPase-Activating Proteins);人类(Humans);肺肿瘤(Lung Neoplasms);肿瘤侵润(Neoplasm Invasiveness);肿瘤抑制蛋白质类(Tumor Suppressor Proteins);ρGTP结合蛋白质类(rho GTP-Binding Proteins)

DOI 10.1186/s12964-020-00635-5

PMID 32900380

发布时间 2021-09-09

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