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Usefulness of current candidate genetic markers to identify childhood cancer patients at risk for platinum-induced ototoxicity: Results of the European PanCareLIFE cohort study.

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作者单位: Department of Pediatric Oncology and Hematology, University Hospital for Children and Adolescents, Lübeck, Germany. [1] Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands; Department of Pediatric Oncology, Erasmus MC - Sophia Children's Hospital, Rotterdam, the Netherlands. [2] Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands. [3] Institute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University Medical Center, Ulm, Germany. [4] Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands. [5] German Childhood Cancer Registry, Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany; Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany. [6] Institute of Epidemiology and Medical Biometry, University of Ulm, Ulm, Germany. [7] Boyne Research Institute, Drogheda, Ireland. [8] Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands; Department of Pediatric Hematology and Oncology, VU Medical Center, Amsterdam, the Netherlands. [9] Department of Neurooncology, Istituto Giannina Gaslini, Genova, Italy. [10] German Childhood Cancer Registry, Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany. [11] Danish Cancer Society Research Center, Childhood Cancer Research Group, Copenhagen, Denmark. [12] Danish Cancer Society Research Center, Childhood Cancer Research Group, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health, Aarhus University, Aarhus, Denmark. [13] Copenhagen University Hospital Rigshospitalet, Department of Pediatrics and Adolescent Medicine, Copenhagen, Denmark. [14] Aarhus University Hospital, Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark. [15] University Hospital Brno, Brno, Czech Republic; International Clinical Research Center (FNUSA-ICRC), Brno, Czech Republic. [16] Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands; Department of Obstetrics and Gynecology, Erasmus MC - Sophia Children's Hospital, the Netherlands. [17] Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands; Department of Pediatric Oncology, Academic Medical Center Amsterdam, Amsterdam, the Netherlands. [18] Department of Children Hemato-Oncology, Motol University Hospital Prague, Prague, Czech Republic. [19] Department of Pediatric Oncology, Hematology, Immunology, Stuttgart Cancer Center, Olgahospital, Stuttgart, Germany. [20] Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland; Paediatric Oncology, Dept. of Paediatrics, Inselspital, University of Bern, Switzerland. [21] Department of Pediatrics, Oncology and Hematology Unit, University Hospital of Geneva, Cansearch Research Laboratory, Geneva University, Switzerland. [22] Department of Otolaryngology, Head and Neck Surgery, Inselspital, University of Berne, Switzerland. [23] Department of Phoniatrics and Pedaudiology, University Hospital Münster, Westphalian Wilhelm University, Münster, Germany. [24] Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands; Department of Pediatric Oncology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. [25] Hospital for Children and Adolescents, University of Erlangen-Nuremberg, Erlangen, Germany. [26] Institute for Social Medicine and Epidemiology, University of Lübeck, Lübeck, Germany. [27] Institute of Clinical Pharmacology, Immanuel Klinik Rüdersdorf, Brandenburg Medical School Theodor Fontane, Germany; Institute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University Medical Center, Ulm, Germany. Electronic address: oliver.zolk@mhb-fontane.de. [28]
DOI 10.1016/j.ejca.2020.07.019
PMID 32905960
发布时间 2021-01-25
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