DEPTOR Prevents Osteoarthritis Development Via Interplay With TRC8 to Reduce Endoplasmic Reticulum Stress in Chondrocytes.

导出 LinkOut

翻译打印收藏纠错

第一作者： Kai,Li

第一单位： Academy of Orthopedics, Guangdong Province, Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases, The Third Affiliated Hospital of Southern Medical University, Guangzhou, China.;State Key Laboratory of Organ Failure Research, Department of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.;Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Guangzhou, China.

作者： Kai,Li ^[1] ; Panpan,Yang ^[2] ; Yuwei,Zhang ^[3] ; Yue,Zhang ^[3] ; He,Cao ^[2] ; Peilin,Liu ^[2] ; Bin,Huang ^[2] ; Song,Xu ^[4] ; Pinglin,Lai ^[2] ; Guanghua,Lei ^[5] ; Jia,Liu ^[6] ; Yujin,Tang ^[6] ; Xiaochun,Bai ^[1] ; Zhipeng,Zou ^[3]

作者单位： Academy of Orthopedics, Guangdong Province, Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases, The Third Affiliated Hospital of Southern Medical University, Guangzhou, China.;State Key Laboratory of Organ Failure Research, Department of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.;Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Guangzhou, China. ^[1] Academy of Orthopedics, Guangdong Province, Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases, The Third Affiliated Hospital of Southern Medical University, Guangzhou, China. ^[2] State Key Laboratory of Organ Failure Research, Department of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China. ^[3] Department of Orthopedics and Arthroplasty, Nanfang Hospital, Southern Medical University, Guangzhou, China. ^[4] Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, China. ^[5] Department of Orthopedics, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China. ^[6]

关键词 DEPTOR ER STRESS OSTEOARTHRITIS TRC8 UBIQUITINATION

主题词动物(Animals);细胞凋亡(Apoptosis);软骨, 关节(Cartilage, Articular);软骨细胞(Chondrocytes);小鼠(Mice);骨关节炎(Osteoarthritis);信号传导(Signal Transduction)

DOI 10.1002/jbmr.4176

PMID 32916025

发布时间 2021-08-09

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交