Unique clinicopathologic and genetic alteration features in early onset colorectal carcinoma compared with age-related colorectal carcinoma: a large cohort next generation sequence analysis.
第一作者:
David,Escobar
第一单位:
Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA.
作者:
主题词
成年人(Adult);发病年龄(Age of Onset);老年人(Aged);老年人, 80以上(Aged, 80 and over);芝加哥(Chicago);I类磷脂酰肌醇3-激酶类(Class I Phosphatidylinositol 3-Kinases);结直肠肿瘤(Colorectal Neoplasms);DNA错配修复(DNA Mismatch Repair);DNA突变分析(DNA Mutational Analysis);DNA修复酶类(DNA Repair Enzymes);女(雌)性(Female);疾病遗传易感性(Genetic Predisposition to Disease);高通量核苷酸序列分析(High-Throughput Nucleotide Sequencing);人类(Humans);免疫组织化学(Immunohistochemistry);男(雄)性(Male);微卫星不稳定性(Microsatellite Instability);突变(Mutation);表型(Phenotype);预后(Prognosis);原癌基因蛋白质B-raf(Proto-Oncogene Proteins B-raf);原癌基因蛋白质类p21(ras)(Proto-Oncogene Proteins p21(ras));青年人(Young Adult);β连环素(beta Catenin)
DOI
10.1016/j.humpath.2020.08.002
PMID
32916163
发布时间
2022-10-03
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Human pathology
37-46页
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