Targetable BRAF and RAF1 Alterations in Advanced Pediatric Cancers.

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第一作者： Andrew,Rankin

第一单位： Foundation Medicine Inc., Cambridge, Massachusetts, USA.

作者： Andrew,Rankin ^[1] ; Adrienne,Johnson ^[1] ; Alison,Roos ^[1] ; Geoffrey,Kannan ^[2] ; Jeffrey,Knipstein ^[3] ; Nicholas,Britt ^[4] ; Mark,Rosenzweig ^[1] ; James,Haberberger ^[4] ; Dean,Pavlick ^[1] ; Eric,Severson ^[4] ; Jo-Anne,Vergilio ^[1] ; Rachel,Squillace ^[1] ; Rachel,Erlich ^[1] ; Pratheesh,Sathyan ^[1] ; Stuart,Cramer ^[5] ; David,Kram ^[6] ; Jeffrey,Ross ^[7] ; Vince,Miller ^[1] ; Prasanth,Reddy ^[1] ; Brian,Alexander ^[1] ; Siraj M,Ali ^[1] ; Shakti,Ramkissoon ^[8]

作者单位： Foundation Medicine Inc., Cambridge, Massachusetts, USA. ^[1] Center for Cancer and Blood Disorders, Pediatric Specialists of Virginia, Falls Church, Virginia, USA. ^[2] Pediatric Hematology/Oncology/BMT, Medical College of Wisconsin, Milwaukee, Wisconsin, USA. ^[3] Foundation Medicine Inc., Morrisville, North, Carolina, USA. ^[4] University of South Carolina School of Medicine, Columbia, South Carolina, USA. ^[5] Wake Forest Pediatric Oncology, Winston-Salem, North Carolina, USA. ^[6] Foundation Medicine Inc., Cambridge, Massachusetts, USA.;SUNY Upstate Medical University, Syracuse, New York, USA. ^[7] Foundation Medicine Inc., Morrisville, North, Carolina, USA.;Wake Forest Comprehensive Cancer Center and Department of Pathology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA. ^[8]

关键词 Biomarkers Brain neoplasms Leukemia Pediatrics Precision medicine Proteins B-raf Proto-oncogene Tumor