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Translocase of the outer mitochondrial membrane complex subunit 20 (TOMM20) facilitates cancer aggressiveness and therapeutic resistance in chondrosarcoma.

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第一作者： Megan E,Roche

第一单位： Department of Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, USA.

作者： Megan E,Roche ^[1] ; Zhao,Lin ^[1] ; Diana,Whitaker-Menezes ^[1] ; Tingting,Zhan ^[2] ; Karoly,Szuhai ^[3] ; Judith V M G,Bovee ^[3] ; John A,Abraham ^[4] ; Wei,Jiang ^[5] ; Ubaldo,Martinez-Outschoorn ^[6] ; Atrayee,Basu-Mallick ^[7]

作者单位： Department of Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, USA. ^[1] Department of Pharmacology, Division of Biostatistics, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, USA. ^[2] Department of Pathology, Leiden University, the Netherlands. ^[3] Department of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, USA. ^[4] Department of Pathology, Anatomy & Cell Biology, Thomas Jefferson University, Philadelphia, USA. ^[5] Department of Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, USA. Electronic address: ubaldo.martinez-outschoorn@jefferson.edu. ^[6] Department of Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, USA. Electronic address: atrayee.basumallick@jefferson.edu. ^[7]

关键词 Apoptosis Chemotherapy resistance Chondrosarcoma Mitochondria Proliferation