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Osteopontin/secreted phosphoprotein-1 behaves as a molecular brake regulating the neuroinflammatory response to chronic viral infection.

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第一作者： Farina J,Mahmud

第一单位： Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.

作者： Farina J,Mahmud ^[1] ; Yong,Du ^[2] ; Elizabeth,Greif ^[1] ; Thomas,Boucher ^[1] ; Robert F,Dannals ^[2] ; William B,Mathews ^[2] ; Martin G,Pomper ^[2] ; Polina,Sysa-Shah ^[2] ; Kelly A,Metcalf Pate ^[3] ; Claire,Lyons ^[3] ; Bess,Carlson ^[3] ; Maria,Chacona ^[1] ; Amanda M,Brown ^[4]

作者单位： Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA. ^[1] Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA. ^[2] Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA. ^[3] Department of Neurology and Neuroscience, Baltimore, USA. abrown76@jh.edu. ^[4]

关键词 DPA-713 Human immunodeficiency virus type-1 Ionized calcium binding adaptor molecule 1 Microglial activation Neuroimaging Neuroinflammation Peripheral benzodiazepine receptor Positron emission tomography Purkinje cells RNAscope