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首页> Journal of controlled release : official journal of the Controlled Release Society> Bile acid-based dual-functional prodrug nanoparticles for bone regeneration through hydrogen peroxide scavenging and osteogenic differentiation of mesenchymal stem cells.

Bile acid-based dual-functional prodrug nanoparticles for bone regeneration through hydrogen peroxide scavenging and osteogenic differentiation of mesenchymal stem cells.

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作者： Yoshie,Arai ^[1] ; Hyoeun,Park ^[1] ; Sunghyun,Park ^[2] ; Dohyun,Kim ^[1] ; Inho,Baek ^[1] ; Lipjeong,Jeong ^[3] ; Byoung Ju,Kim ^[1] ; Kwideok,Park ^[4] ; Dongwon,Lee ^[5] ; Soo-Hong,Lee ^[6]

作者单位： Department of Medical Biotechnology, Dongguk University, 04620 Seoul, South Korea. ^[1] Department of Biomedical Science, CHA University, CHA Biocomplex, 13488 Gyeonggi-do, South Korea. ^[2] Department of BIN Convergence Technology, Jeonbuk National University, 54896 Jeonbuk, South Korea. ^[3] Center for Biomaterials, Korea Institute of Science and Technology (KIST), 02792 Seoul, South Korea. ^[4] Department of BIN Convergence Technology, Jeonbuk National University, 54896 Jeonbuk, South Korea. Electronic address: dlee@chonbuk.ac.kr. ^[5] Department of Medical Biotechnology, Dongguk University, 04620 Seoul, South Korea. Electronic address: soohong@dongguk.edu. ^[6]

关键词 Bile acid Bone tissue regeneration Hydrogen peroxide Mesenchymal stem cells Nanoparticles Polymeric prodrug

主题词动物(Animals);胆汁酸类和盐类(Bile Acids and Salts);骨再生(Bone Regeneration);细胞分化(Cell Differentiation);过氧化氢(Hydrogen Peroxide);间质干细胞(Mesenchymal Stem Cells);纳米粒子(Nanoparticles);骨生成(Osteogenesis);药物前体(Prodrugs);大鼠(Rats)

DOI 10.1016/j.jconrel.2020.09.023

PMID 32946872

发布时间 2021-06-17

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Journal of controlled release

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