Autophagy induction promotes renal cyst growth in polycystic kidney disease.

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第一作者： Eun Ji,Lee

第一单位： Department of Biological Science, Sookmyung Women's University, Seoul 04310, Republic of Korea.

作者： Eun Ji,Lee ^[1] ; Je Yeong,Ko ^[1] ; Sumin,Oh ^[1] ; Jaehee,Jun ^[1] ; Hyowon,Mun ^[1] ; Chae Ji,Lim ^[2] ; Seungwoon,Seo ^[2] ; Hyuk Wan,Ko ^[3] ; Hyunho,Kim ^[4] ; Yun Kyu,Oh ^[5] ; Curie,Ahn ^[6] ; Minyong,Kang ^[7] ; Min Jung,Kim ^[1] ; Kyung Hyun,Yoo ^[1] ; Goo Taeg,Oh ^[8] ; Jong Hoon,Park ^[9]

作者单位： Department of Biological Science, Sookmyung Women's University, Seoul 04310, Republic of Korea. ^[1] Department of Biology, Ewha Womans University, Seoul 03760, Republic of Korea. ^[2] Department of Biochemistry, Yonsei University, Seoul 03722, Republic of Korea. ^[3] Center for Medical Innovation, Biomedical Research Institute, Seoul National University Hospital, Seoul 03082, Republic of Korea. ^[4] Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul 07061, Republic of Korea. ^[5] Department of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea. ^[6] Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Republic of Korea. ^[7] Department of Biology, Ewha Womans University, Seoul 03760, Republic of Korea. Electronic address: gootaeg@ewha.ac.kr. ^[8] Department of Biological Science, Sookmyung Women's University, Seoul 04310, Republic of Korea. Electronic address: parkjh@sookmyung.ac.kr. ^[9]

关键词 Autophagy Ift46 PKD Polycystic kidney

主题词动物(Animals);自噬(Autophagy);细胞系(Cell Line);计算生物学(Computational Biology);囊肿(Cysts);疾病模型, 动物(Disease Models, Animal);疾病易感性(Disease Susceptibility);细胞外信号调节MAP激酶类(Extracellular Signal-Regulated MAP Kinases);基因表达谱(Gene Expression Profiling);疾病遗传易感性(Genetic Predisposition to Disease);人类(Humans);小鼠(Mice);小鼠, 转基因(Mice, Transgenic);磷酰化(Phosphorylation);多囊肾疾病(Polycystic Kidney Diseases);信号传导(Signal Transduction);TOR丝氨酸-苏氨酸激酶(TOR Serine-Threonine Kinases);斑马鱼(Zebrafish)

DOI 10.1016/j.ebiom.2020.102986

PMID 32949996

发布时间 2021-12-04

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Autophagy induction promotes renal cyst growth in polycystic kidney disease.

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Autophagy induction promotes renal cyst growth in polycystic kidney disease.

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