Toward Developing Discriminating Dissolution Methods for Formulations Containing Nanoparticulates in Solution: The Impact of Particle Drift and Drug Activity in Solution.

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作者： Freddy A,Arce ^[1] ; Nico,Setiawan ^[2] ; Heather R,Campbell ^[1] ; Xingyu,Lu ^[3] ; Matthew J,Nethercott ^[4] ; Paul,Bummer ^[5] ; Yongchao,Su ^[1] ; Patrick J,Marsac ^[3]

作者单位： Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536, United States. ^[1] Albany Molecular Research Inc., West Lafayette, Indiana 47906, United States. ^[2] Pharmaceutical Sciences, Merck & Co., Kenilworth, New Jersey 07033, United States. ^[3] Key Laboratory of Precise Synthesis of Functional Molecules of Zhejiang Province, School of Science, Westlake University, Hangzhou, Zhejiang 310024, China. ^[4] Kansas Analytical Services, LLC, Loveland, Colorado 80537, United States. ^[5] Division of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, The University of Texas at Austin, Austin, Texas 78712, United States. ^[6] Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, West Lafayette, Indiana 47907, United States. ^[7]