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Clinical and analytical validation of FoundationOne Liquid CDx, a novel 324-Gene cfDNA-based comprehensive genomic profiling assay for cancers of solid tumor origin.

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第一作者： Ryan,Woodhouse

第一单位： Regulatory Affairs, Foundation Medicine, Inc, Cambridge, Massachusetts, United States of America.

作者： Ryan,Woodhouse ^[1] ; Meijuan,Li ^[2] ; Jason,Hughes ^[3] ; David,Delfosse ^[4] ; Joel,Skoletsky ^[4] ; Pei,Ma ^[2] ; Wei,Meng ^[2] ; Ninad,Dewal ^[2] ; Coren,Milbury ^[4] ; Travis,Clark ^[5] ; Amy,Donahue ^[6] ; Dan,Stover ^[7] ; Mark,Kennedy ^[3] ; Jennifer,Dacpano-Komansky ^[8] ; Christine,Burns ^[4] ; Christine,Vietz ^[9] ; Brian,Alexander ^[10] ; Priti,Hegde ^[6] ; Lucas,Dennis ^[11]

作者单位： Regulatory Affairs, Foundation Medicine, Inc, Cambridge, Massachusetts, United States of America. ^[1] Biometrics and Biomarkers, Foundation Medicine, Inc, Cambridge, Massachusetts, United States of America. ^[2] Computational Biology, Foundation Medicine, Inc, Cambridge, Massachusetts, United States of America. ^[3] Development Operations, Foundation Medicine, Inc, Cambridge, Massachusetts, United States of America. ^[4] Formerly Assay Development, Foundation Medicine, Inc, Cambridge, Massachusetts, United States of America. ^[5] Assay Development, Foundation Medicine, Inc, Cambridge, Massachusetts, United States of America. ^[6] Laboratory Operations, Foundation Medicine, Inc, Cambridge, Massachusetts, United States of America. ^[7] Medical Device Global Regulatory Affairs, Novartis Corporation, Cambridge, Massachusetts, United States of America. ^[8] Product Development, Foundation Medicine, Inc, Cambridge, Massachusetts, United States of America. ^[9] Clinical Development, Foundation Medicine, Inc, Cambridge, Massachusetts, United States of America. ^[10] Franchise Development, Foundation Medicine, Inc, Cambridge, Massachusetts, United States of America. ^[11]