A novel germline EGFR variant p.R831H causes predisposition to familial CDK12-mutant prostate cancer with tandem duplicator phenotype.

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作者： Kaiyu,Qian ^[1] ; Gang,Wang ^[2] ; Lingao,Ju ^[2] ; Jiyan,Liu ^[3] ; Yongwen,Luo ^[4] ; Yejinpeng,Wang ^[4] ; Tianchen,Peng ^[4] ; Fangjin,Chen ^[5] ; Yi,Zhang ^[6] ; Yu,Xiao ^[7] ; Xinghuan,Wang ^[8]

作者单位： Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.;Department of Biological Repositories, Zhongnan Hospital of Wuhan University, Wuhan, China.;Human Genetic Resources Preservation Center of Hubei Province, Wuhan, China. ^[1] Department of Biological Repositories, Zhongnan Hospital of Wuhan University, Wuhan, China.;Human Genetic Resources Preservation Center of Hubei Province, Wuhan, China.;Laboratory of Precision Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China. ^[2] Department of Biotherapy, Cancer Center, West China Hospital of Sichuan University, Chengdu, China. ^[3] Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China. ^[4] Center of Life Sciences, Peking University, Beijing, China. ^[5] Center of Life Sciences, Peking University, Beijing, China. zy@eulertechnology.com.;Euler Technology, Beijing, China. zy@eulertechnology.com. ^[6] Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.;Department of Biological Repositories, Zhongnan Hospital of Wuhan University, Wuhan, China.;Human Genetic Resources Preservation Center of Hubei Province, Wuhan, China.;Laboratory of Precision Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China. ^[7] Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China. wangxinghuan@whu.edu.cn.;Medical Research Institute, Wuhan University, Wuhan, China. wangxinghuan@whu.edu.cn. ^[8]