CRISPR-based biosensing is prospective for rapid and sensitive diagnosis of pediatric tuberculosis.

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作者： Chunyang,Lyu ^[1] ; Hua,Shi ^[1] ; Yali,Cui ^[1] ; Mingyuan,Li ^[1] ; Ziyi,Yan ^[1] ; Lingyi,Yan ^[1] ; Yongmei,Jiang ^[2]

作者单位： Department of Laboratory Medicine, West China Second Hospital, Sichuan University, Chengdu, Sichuan, China; Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, Sichuan, China. ^[1] Department of Laboratory Medicine, West China Second Hospital, Sichuan University, Chengdu, Sichuan, China; Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, Sichuan, China. Electronic address: jiangyongmei-1@163.com. ^[2]

关键词 Biosensing platforms CRISPR-Cas Childhood tuberculosis Diagnosis Nucleic acid detection

主题词诊断试验, 常规(Diagnostic Tests, Routine);人类(Humans);结核分枝杆菌(Mycobacterium tuberculosis);前瞻性研究(Prospective Studies);敏感性与特异性(Sensitivity and Specificity);结核(Tuberculosis)

DOI 10.1016/j.ijid.2020.09.1428

PMID 32987180

发布时间 2021-03-01

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