Development and Validation of a Fully GMP-Compliant Process for Manufacturing Stromal Vascular Fraction: A Cost-Effective Alternative to Automated Methods.

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作者： Pauline,François ^[1] ; Laurent,Giraudo ^[2] ; Julie,Veran ^[1] ; Baptiste,Bertrand ^[1] ; Chloé,Dumoulin ^[3] ; Houssein,Aboudou ^[1] ; Fanny,Grimaud ^[1] ; Marie,Vogtensperger ^[1] ; Mélanie,Velier ^[4] ; Laurent,Arnaud ^[2] ; Luc,Lyonnet ^[5] ; Stéphanie,Simoncini ^[5] ; Benjamin,Guillet ^[5] ; Françoise,Dignat-George ^[2] ; Jérémy,Magalon ^[2] ; Florence,Sabatier ^[6]

作者单位： Cell Therapy Department, Hôpital de la Conception, AP-HM, INSERM CIC BT 1409, 13005 Marseille, France. ^[1] Aix Marseille University, INSERM, INRAE, C2VN, 13005 Marseille, France. ^[2] Plastic Surgery Department, Hôpital de la Conception, AP-HM, 13005 Marseille, France. ^[3] French Military Blood Institute, 92140 Clamart, France. ^[4] Laboratory of Hematology and Vascular Biology, Hôpital de la Conception, AP-HM, 13005 Marseille, France. ^[5] CERIMED, Aix Marseille University, AP-HM, 13005 Marseille, France. ^[6]

关键词 GMP-compliant manufacturing cell therapy stromal vascular fraction wound healing

主题词脂肪组织(Adipose Tissue);动物(Animals);自动化(Automation);细胞培养技术(Cell Culture Techniques);胶原酶类(Collagenases);费用效益分析(Cost-Benefit Analysis);疾病模型, 动物(Disease Models, Animal);女(雌)性(Female);人类(Humans);缺血(Ischemia);动力学(Kinetics);小鼠, 裸(Mice, Nude);新生血管化, 生理性(Neovascularization, Physiologic);间质细胞(Stromal Cells);底物特异性(Substrate Specificity)

DOI 10.3390/cells9102158

PMID 32987708

发布时间 2021-04-05

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Cells

2020年9卷10期

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Development and Validation of a Fully GMP-Compliant Process for Manufacturing Stromal Vascular Fraction: A Cost-Effective Alternative to Automated Methods.

Cells

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Development and Validation of a Fully GMP-Compliant Process for Manufacturing Stromal Vascular Fraction: A Cost-Effective Alternative to Automated Methods.

Cells

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Cells

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