CtIP-mediated DNA resection is dispensable for IgH class switch recombination by alternative end-joining.

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作者： Xiaobin S,Wang ^[1] ; Junfei,Zhao ^[2] ; Foon,Wu-Baer ^[3] ; Zhengping,Shao ^[1] ; Brian J,Lee ^[1] ; Olivia M,Cupo ^[1] ; Raul,Rabadan ^[1] ; Jean,Gautier ^[3] ; Richard,Baer ^[4] ; Shan,Zha ^[1]

作者单位： Institute for Cancer Genetics, Vagelos College for Physicians and Surgeons, Columbia University, New York, NY 10032. ^[1] Graduate Program of Pathobiology and Molecular Medicine, Vagelos College for Physicians and Surgeons, Columbia University, New York, NY 10032. ^[2] Program for Mathematical Genomics, Department of Systems Biology, Columbia University, New York, NY 10032. ^[3] Department of Biomedical Informatics, Columbia University, New York, NY 10032. ^[4] Department of Genetics and Development, Vagelos College for Physicians and Surgeons, Columbia University, New York, NY 10032. ^[5] Department of Pathology and Cell Biology, Herbert Irvine Comprehensive Cancer Center, Vagelos College for Physicians and Surgeons, Columbia University, New York, NY 10032. ^[6] Institute for Cancer Genetics, Vagelos College for Physicians and Surgeons, Columbia University, New York, NY 10032; sz2296@cumc.columbia.edu. ^[7] Division of Pediatric Hematology, Oncology, and Stem Cell Transplantation, Department of Pediatrics, Vagelos College for Physicians and Surgeons, Columbia University, New York, NY 10032. ^[8] Department of Immunology and Microbiology, Vagelos College for Physicians and Surgeons, Columbia University, New York, NY 10032. ^[9]

关键词 CtIP alternative end-joining class switch recombination