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Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.

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第一作者: Luca,Piccoli
第一单位: Humabs BioMed SA, Vir Biotechnology, 6500 Bellinzona, Switzerland.
作者单位: Humabs BioMed SA, Vir Biotechnology, 6500 Bellinzona, Switzerland. [1] Department of Biochemistry, University of Washington, Seattle, WA 98195, USA. [2] Department of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institut Pasteur and CNRS UMR 3569, Unité de Virologie Structurale, 75015 Paris, France. [3] Vir Biotechnology, San Francisco, CA 94158, USA. [4] Molecular Biology Consortium, Advanced Light Source, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. [5] Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland. [6] Division of Primary Care, Geneva University Hospitals, 1205 Geneva, Switzerland; Faculty of Biomedical Sciences, Università della Svizzera italiana, 6900 Lugano, Switzerland. [7] Clinic of Internal Medicine and Infectious Diseases, Clinica Luganese Moncucco, 6900 Lugano, Switzerland. [8] III Division of Infectious Diseases, ASST Fatebenefratelli Sacco, Luigi Sacco Hospital, 20157 Milan, Italy. [9] Independent Physician, 6500 Bellinzona, Switzerland. [10] Institute of Public Health, Università della Svizzera italiana, 6900 Lugano, Switzerland. [11] Faculty of Biomedical Sciences, Università della Svizzera italiana, 6900 Lugano, Switzerland; Division of Clinical Pharmacology and Toxicology, Institute of Pharmacological Sciences of Southern Switzerland, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland; Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, 8091 Zurich, Switzerland. [12] Division of Infectious Diseases, Ente Ospedaliero Cantonale, Ospedale Civico and Ospedale Italiano, 6900 Lugano, Switzerland. [13] Division of Infectious Diseases, Ente Ospedaliero Cantonale, Ospedale Regionale Bellinzona e Valli and Ospedale Regionale, 6600 Locarno, Switzerland. [14] Department of Nephrology, Ospedale Civico Lugano, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland; Prince of Wales Hospital Clinical School, University of New South Wales, Sydney, NSW 2052, Australia. [15] Humabs BioMed SA, Vir Biotechnology, 6500 Bellinzona, Switzerland. Electronic address: dcorti@vir.bio. [16] Department of Biochemistry, University of Washington, Seattle, WA 98195, USA. Electronic address: dveesler@uw.edu. [17]
DOI 10.1016/j.cell.2020.09.037
PMID 32991844
发布时间 2024-09-22
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Cell

Cell

2020年183卷4期

1024-1042.e21页

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