Prerandomization run-in periods in randomized controlled trials of chronic diseases: a methodological study.

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作者： David,Collister ^[1] ; Jennifer C,Rodrigues ^[2] ; Lawrence,Mbuagbaw ^[2] ; P J,Devereaux ^[3] ; Gordon,Guyatt ^[2] ; William,Herrington ^[4] ; Michael,Walsh ^[3]

作者单位： Department of Health Research Methods, Evidence and Impact, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada; Population Health Research Institute, 237 Barton Street East, Hamilton, Ontario, Canada. Electronic address: dtcollister@gmail.com. ^[1] Department of Health Research Methods, Evidence and Impact, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada. ^[2] Department of Health Research Methods, Evidence and Impact, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada; Population Health Research Institute, 237 Barton Street East, Hamilton, Ontario, Canada. ^[3] Medical Research Council Population Health Research Unit at the University of Oxford, Clinical Trial Service Unit and Epidemiological Studies Unit, Richard Doll Building, Old Road Campus, Oxford OX3 7LF, UK. ^[4]

关键词 Chronic disease Meta-epidemiology Pharmacologic therapies Prerandomization Randomized controlled trials Run-in periods

主题词慢性病(Chronic Disease);流行病学研究设计(Epidemiologic Research Design);人类(Humans);随机对照试验(主题)(Randomized Controlled Trials as Topic)

DOI 10.1016/j.jclinepi.2020.09.035

PMID 33002638

发布时间 2021-04-14

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