换一批Design, synthesis, and multitargeted profiling of N-benzylpyrrolidine derivatives for the treatment of Alzheimer's disease.
第一作者：
Priyanka Kumari,Choubey
第一单位：
Pharmaceutical Chemistry Research Laboratory, Department of Pharmaceutical Engineering & Technology, Indian Institute of Technology (Banaras Hindu University), Varanasi 221005, India.
作者：
医学主题词
乙酰胆碱酯酶(Acetylcholinesterase);阿尔茨海默病(Alzheimer Disease);遗忘(Amnesia);淀粉样β肽类(Amyloid beta-Peptides);动物(Animals);丁酰胆碱酯酶(Butyrylcholinesterase);细胞系, 肿瘤(Cell Line, Tumor);胆碱酯酶抑制剂(Cholinesterase Inhibitors);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物设计(Drug Design);女(雌)性(Female);人类(Humans);男(雄)性(Male);模型, 分子(Models, Molecular);分子结构(Molecular Structure);神经保护药(Neuroprotective Agents);吡咯烷类(Pyrrolidines);大鼠(Rats);大鼠, Wistar(Rats, Wistar);氢溴酸东莨菪碱(Scopolamine Hydrobromide);构效关系(Structure-Activity Relationship)
DOI
10.1016/j.bmc.2020.115721
PMID
33007563
发布时间
2021-07-21
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