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The reliability of a deep learning model in clinical out-of-distribution MRI data: A multicohort study.

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作者单位: Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden. Electronic address: gustav.martensson@ki.se. [1] Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden. [2] Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Department of Radiology, Karolinska University Hospital, Stockholm, Sweden. [3] Centre for Age-Related Medicine, Stavanger University Hospital, Stavanger, Norway; Stavanger Medical Imaging Laboratory (SMIL), Department of Radiology, Stavanger University Hospital, Stavanger, Norway; Department of Electrical Engineering and Computer Science, University of Stavanger, Stavanger, Norway. [4] Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy. [5] 1st Department of Neurology, Medical Faculty, St. Anne's Hospital and CEITEC, Masaryk University, Brno, Czech Republic. [6] Department of Neuroscience Imaging and Clinical Sciences and CESI, University G d'Annunzio of Chieti-Pescara, Chieti, Italy. [7] Department of Neuroscience (DINOGMI), University of Genoa and Neurology Clinics, Polyclinic San Martino Hospital, Genoa, Italy. [8] Department of Neurology, University Medical Centre Ljubljana, Medical faculty, University of Ljubljana, Slovenia. [9] Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK. [10] Memory Clinic, Department of Neurology, Charles University, 2nd Faculty of Medicine and Motol University Hospital, Prague, Czech Republic. [11] Landspitali University Hospital, Reykjavik, Iceland. [12] Movement Disorders Unit, Neurology Department, Sant Pau Hospital, Barcelona, Spain; Institut d'Investigacions Biomédiques Sant Pau (IIB-Sant Pau), Barcelona, Spain; Centro de Investigación en Red-Enfermedades Neurodegenerativas (CIBERNED), Barcelona, Spain; Universitat Autónoma de Barcelona (U.A.B.), Barcelona, Spain. [13] Day Hospital of Geriatrics, Memory Resource and Research Centre (CM2R) of Strasbourg, Department of Geriatrics, Hôpitaux Universitaires de Strasbourg, Strasbourg, France; University of Strasbourg and French National Centre for Scientific Research (CNRS), ICube Laboratory and Fédération de Médecine Translationnelle de Strasbourg (FMTS), Team Imagerie Multimodale Intégrative en Santé (IMIS)/ICONE, Strasbourg, France. [14] Department of Neuroscience, University of Padua, Padua & Fondazione Ospedale San Camillo, Venezia, Venice, Italy. [15] Institute of Gerontology and Geriatrics, University of Perugia, Perugia, Italy. [16] UMR INSERM 1027, gerontopole, CHU, University of Toulouse, France. [17] 3rd Department of Neurology, Memory and Dementia Unit, Aristotle University of Thessaloniki, Thessaloniki, Greece. [18] Medical University of Lodz, Lodz, Poland. [19] Institute of Clinical Medicine, Neurology, University of Eastern Finland, Finland; Neurocenter, Neurology, Kuopio University Hospital, Kuopio, Finland. [20] Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK. [21] NIHR Biomedical Research Centre for Mental Health, London, UK; NIHR Biomedical Research Unit for Dementia, London, UK; Department of Neuroimaging, Centre for Neuroimaging Sciences, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. [22] Centre for Age-Related Medicine, Stavanger University Hospital, Stavanger, Norway; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. [23] Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden; Department of Neuroimaging, Centre for Neuroimaging Sciences, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. [24]
DOI 10.1016/j.media.2020.101714
PMID 33007638
发布时间 2021-06-23
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