换一批Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology.
第一作者：
Anna,Golebiewska
第一单位：
NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 84, Val Fleuri, 1526, Luxembourg, Luxembourg.
作者：
Anna,Golebiewska [1]
;
Ann-Christin,Hau [1]
;
Anaïs,Oudin [1]
;
Daniel,Stieber [2]
;
Yahaya A,Yabo [3]
;
Virginie,Baus [1]
;
Vanessa,Barthelemy [1]
;
Eliane,Klein [1]
;
Sébastien,Bougnaud [1]
;
Olivier,Keunen [4]
;
May,Wantz [1]
;
Alessandro,Michelucci [5]
;
Virginie,Neirinckx [1]
;
Arnaud,Muller [6]
;
Tony,Kaoma [6]
;
Petr V,Nazarov [6]
;
Francisco,Azuaje [6]
;
Alfonso,De Falco [7]
;
Ben,Flies [8]
;
Lorraine,Richart [9]
;
Suresh,Poovathingal [10]
;
Thais,Arns [10]
;
Kamil,Grzyb [10]
;
Andreas,Mock [11]
;
Christel,Herold-Mende [12]
;
Anne,Steino [13]
;
Dennis,Brown [13]
;
Patrick,May [10]
;
Hrvoje,Miletic [14]
;
Tathiane M,Malta [15]
;
Houtan,Noushmehr [15]
;
Yong-Jun,Kwon [16]
;
Winnie,Jahn [17]
;
Barbara,Klink [18]
;
Georgette,Tanner [19]
;
Lucy F,Stead [19]
;
Michel,Mittelbronn [20]
;
Alexander,Skupin [10]
;
Frank,Hertel [21]
;
Rolf,Bjerkvig [22]
;
Simone P,Niclou [23]
作者单位：
NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 84, Val Fleuri, 1526, Luxembourg, Luxembourg.
[1]
NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 84, Val Fleuri, 1526, Luxembourg, Luxembourg.;National Center of Genetics, Laboratoire National de Santé, 3555, Dudelange, Luxembourg.
[2]
NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 84, Val Fleuri, 1526, Luxembourg, Luxembourg.;Faculty of Science, Technology and Medicine, University of Luxembourg, 4367, Belvaux, Luxembourg.
[3]
NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 84, Val Fleuri, 1526, Luxembourg, Luxembourg.;Quantitative Biology Unit, Luxembourg Institute of Health, 1445, Strassen, Luxembourg.
[4]
NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 84, Val Fleuri, 1526, Luxembourg, Luxembourg.;Neuro-Immunology Group, Department of Oncology, Luxembourg Institute of Health, 1526, Luxembourg, Luxembourg.;Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 4367, Belvaux, Luxembourg.
[5]
Quantitative Biology Unit, Luxembourg Institute of Health, 1445, Strassen, Luxembourg.
[6]
National Center of Genetics, Laboratoire National de Santé, 3555, Dudelange, Luxembourg.;Faculty of Science, Technology and Medicine, University of Luxembourg, 4367, Belvaux, Luxembourg.;Luxembourg Center of Neuropathology, Luxembourg, Luxembourg.
[7]
National Center of Genetics, Laboratoire National de Santé, 3555, Dudelange, Luxembourg.
[8]
Faculty of Science, Technology and Medicine, University of Luxembourg, 4367, Belvaux, Luxembourg.;Luxembourg Center of Neuropathology, Luxembourg, Luxembourg.;National Center of Pathology, Laboratoire National de Santé, 3555, Dudelange, Luxembourg.;Department of Oncology, Luxembourg Institute of Health, 1526, Luxembourg, Luxembourg.
[9]
Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 4367, Belvaux, Luxembourg.
[10]
Division of Experimental Neurosurgery, Department of Neurosurgery, University of Heidelberg, 69120, Heidelberg, Germany.;Department of Medical Oncology, National Center for Tumor Diseases (NCT) Heidelberg, Heidelberg University Hospital, 69120, Heidelberg, Germany.;German Cancer Research Center (DKFZ) Heidelberg, 69120, Heidelberg, Germany.;German Cancer Consortium (DKTK), 69120, Heidelberg, Germany.
[11]
Division of Experimental Neurosurgery, Department of Neurosurgery, University of Heidelberg, 69120, Heidelberg, Germany.
[12]
DelMar Pharmaceuticals, Inc., Vancouver, BC, Canada.;DelMar Pharmaceuticals, Inc., Menlo Park, CA, USA.
[13]
Department of Biomedicine, University of Bergen, 5019, Bergen, Norway.;Department of Pathology, Haukeland University Hospital, Bergen, Norway.
[14]
Department of Neurosurgery, Henry Ford Health System, Detroit, MI, 48202, USA.
[15]
Department of Oncology, Luxembourg Institute of Health, 1526, Luxembourg, Luxembourg.
[16]
German Cancer Consortium (DKTK), 01307, Dresden, Germany.;Core Unit for Molecular Tumor Diagnostics (CMTD), National Center for Tumor Diseases (NCT), 01307, Dresden, Germany.
[17]
National Center of Genetics, Laboratoire National de Santé, 3555, Dudelange, Luxembourg.;Department of Oncology, Luxembourg Institute of Health, 1526, Luxembourg, Luxembourg.;German Cancer Consortium (DKTK), 01307, Dresden, Germany.;Core Unit for Molecular Tumor Diagnostics (CMTD), National Center for Tumor Diseases (NCT), 01307, Dresden, Germany.;Institute for Clinical Genetics, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany.
[18]
Leeds Institute of Medical Research at St James's, St James's University Hospital, Leeds, UK.
[19]
Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 4367, Belvaux, Luxembourg.;Luxembourg Center of Neuropathology, Luxembourg, Luxembourg.;National Center of Pathology, Laboratoire National de Santé, 3555, Dudelange, Luxembourg.;Department of Oncology, Luxembourg Institute of Health, 1526, Luxembourg, Luxembourg.
[20]
Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 4367, Belvaux, Luxembourg.;Department of Neurosurgery, Centre Hospitalier Luxembourg, 1210, Luxembourg, Luxembourg.
[21]
NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 84, Val Fleuri, 1526, Luxembourg, Luxembourg.;Department of Biomedicine, University of Bergen, 5019, Bergen, Norway.
[22]
NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 84, Val Fleuri, 1526, Luxembourg, Luxembourg. simone.niclou@lih.lu.;Department of Biomedicine, University of Bergen, 5019, Bergen, Norway. simone.niclou@lih.lu.
[23]
医学主题词
动物(Animals);脑肿瘤(Brain Neoplasms);胶质母细胞瘤(Glioblastoma);神经胶质瘤(Glioma);人类(Humans);小鼠(Mice);肿瘤复发, 局部(Neoplasm Recurrence, Local);类器官(Organoids);大鼠(Rats)
DOI
10.1007/s00401-020-02226-7
PMID
33009951
发布时间
2024-03-30
- 浏览0
Acta neuropathologica
Acta neuropathologica
919-949页
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