Accumulation of neurofibrillary tangles and activated microglia is associated with lower neuron densities in the aphasic variant of Alzheimer's disease.

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作者： Daniel T,Ohm ^[1] ; Angela J,Fought ^[2] ; Adam,Martersteck ^[1] ; Christina,Coventry ^[1] ; Jaiashre,Sridhar ^[1] ; Tamar,Gefen ^[3] ; Sandra,Weintraub ^[3] ; Eileen,Bigio ^[4] ; M-Marsel,Mesulam ^[5] ; Emily,Rogalski ^[3] ; Changiz,Geula ^[1]

作者单位： Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University Feinberg School of Medicine, Chicago, IL. ^[1] Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL. ^[2] Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University Feinberg School of Medicine, Chicago, IL.;Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL. ^[3] Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University Feinberg School of Medicine, Chicago, IL.;Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL. ^[4] Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University Feinberg School of Medicine, Chicago, IL.;Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL. ^[5]

关键词 Alzheimer’s disease activated microglia neurofibrillary tangles neurons primary progressive aphasia