The interplay between host genetics and the gut microbiome reveals common and distinct microbiome features for complex human diseases.

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作者： Fengzhe,Xu ^[1] ; Yuanqing,Fu ^[1] ; Ting-Yu,Sun ^[2] ; Zengliang,Jiang ^[3] ; Zelei,Miao ^[1] ; Menglei,Shuai ^[2] ; Wanglong,Gou ^[1] ; Chu-Wen,Ling ^[1] ; Jian,Yang ^[1] ; Jun,Wang ^[3] ; Yu-Ming,Chen ^[4] ; Ju-Sheng,Zheng ^[5]

作者单位： Zhejiang Provincial Laboratory of Life Sciences and Biomedicine, Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China. ^[1] Institute of Basic Medical Sciences, Westlake Institute for Advanced Study, Hangzhou, China. ^[2] Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, China. ^[3] Institute for Molecular Bioscience, The University of Queensland, QLD, Brisbane, Australia. ^[4] Institute for Advanced Research, Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China. ^[5] CAS Key Laboratory for Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China. junwang@im.ac.cn. ^[6] Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, China. chenyum@mail.sysu.edu.cn. ^[7] Zhejiang Provincial Laboratory of Life Sciences and Biomedicine, Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China. zhengjusheng@westlake.edu.cn. ^[8] Institute of Basic Medical Sciences, Westlake Institute for Advanced Study, Hangzhou, China. zhengjusheng@westlake.edu.cn. ^[9] MRC Epidemiology Unit, University of Cambridge, Cambridge, UK. zhengjusheng@westlake.edu.cn. ^[10]

关键词 Bidirectional Mendelian randomization analyses Disease-microbiome features Gut microbiome Host genetics

主题词成年人(Adult);老年人(Aged);动物(Animals);病例对照研究(Case-Control Studies);疾病(Disease);女(雌)性(Female);全基因组关联研究(Genome-Wide Association Study);人类(Humans);白血病, 髓系, 慢性, BCR-ABL阳性(Leukemia, Myelogenous, Chronic, BCR-ABL Positive);红斑狼疮, 系统性(Lupus Erythematosus, Systemic);男(雄)性(Male);中年人(Middle Aged)

DOI 10.1186/s40168-020-00923-9

PMID 33032658

发布时间 2024-03-29

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Microbiome

2020年8卷1期

145页

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The interplay between host genetics and the gut microbiome reveals common and distinct microbiome features for complex human diseases.

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The interplay between host genetics and the gut microbiome reveals common and distinct microbiome features for complex human diseases.

Microbiome

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Microbiome

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