BRAFV 600E or mutant MAP2K1 human CD34+ cells establish Langerhans cell-like histiocytosis in immune-deficient mice.

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作者： Anahita,Rafiei ^[1] ; C Matthias,Wilk ^[1] ; Patrick M,Helbling ^[1] ; Renier,Myburgh ^[1] ; Yasuyuki,Saito ^[1] ; Eugenia,Haralambieva ^[2] ; Davide,Soldini ^[3] ; Rikhia,Chakraborty ^[3] ; Miriam,Merad ^[4] ; Carl E,Allen ^[5] ; Cesar,Nombela-Arrieta ^[4] ; Markus G,Manz ^[1]

作者单位： Department of Medical Oncology and Hematology, University Hospital and University of Zurich, Zurich, Switzerland. ^[1] Division of Molecular and Cellular Signaling, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Japan. ^[2] Department of Pathology, University Hospital and University of Zurich, Zurich, Switzerland. ^[3] Baylor College of Medicine, Texas Children's Hospital, Texas Children's Cancer Center, Houston, TX; and. ^[4] Precision Immunology Institute and Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY. ^[5]

主题词动物(Animals);组织细胞增多症(Histiocytosis);组织细胞增多症, 郎格尔汉斯细胞(Histiocytosis, Langerhans-Cell);人类(Humans);郎格尔汉斯细胞(Langerhans Cells);MAP激酶激酶1(MAP Kinase Kinase 1);小鼠(Mice)

DOI 10.1182/bloodadvances.2020001926

PMID 33035332

发布时间 2022-07-16

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Blood advances

2020年4卷19期

4912-4917页

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BRAFV 600E or mutant MAP2K1 human CD34+ cells establish Langerhans cell-like histiocytosis in immune-deficient mice.

Blood advances

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Blood advances

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BRAFV 600E or mutant MAP2K1 human CD34+ cells establish Langerhans cell-like histiocytosis in immune-deficient mice.

Blood advances

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Blood advances

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