Monocytic Myeloid-Derived Suppressor Cells Underpin Resistance to Adoptive T Cell Therapy in Nasopharyngeal Carcinoma.

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作者： Richard,Hopkins ^[1] ; Wenwei,Xiang ^[2] ; Damien,Marlier ^[2] ; Veonice Bijin,Au ^[3] ; Qianting,Ching ^[3] ; Lynn Xue,Wu ^[3] ; Rujun,Guan ^[2] ; Bernett,Lee ^[4] ; Whay-Kuang,Chia ^[5] ; Who-Whong,Wang ^[6] ; Joseph,Wee ^[5] ; Joanna,Ng ^[6] ; Rachael,Cheong ^[5] ; Shuting,Han ^[5] ; Axel,Chu ^[5] ; Chit Lai,Chee ^[5] ; Timothy,Shuen ^[5] ; Michael,Podinger ^[4] ; Alexander,Lezhava ^[7] ; Han Chong,Toh ^[8] ; John E,Connolly ^[9]

作者单位： Institute of Molecular and Cell Biology, A∗STAR, Singapore 138673, Singapore; Tessa Therapeutics, Singapore 038982, Singapore. ^[1] Tessa Therapeutics, Singapore 038982, Singapore. ^[2] Institute of Molecular and Cell Biology, A∗STAR, Singapore 138673, Singapore. ^[3] Singapore Immunology Network, Singapore 138648, Singapore. ^[4] National Cancer Centre Singapore, Singapore 169610, Singapore. ^[5] Tessa Therapeutics, Singapore 038982, Singapore; National Cancer Centre Singapore, Singapore 169610, Singapore. ^[6] Genome Institute of Singapore, A∗STAR, Singapore 138672, Singapore. ^[7] Institute of Molecular and Cell Biology, A∗STAR, Singapore 138673, Singapore; Tessa Therapeutics, Singapore 038982, Singapore; National Cancer Centre Singapore, Singapore 169610, Singapore. Electronic address: toh.han.chong@singhealth.com.sg. ^[8] Institute of Molecular and Cell Biology, A∗STAR, Singapore 138673, Singapore; Tessa Therapeutics, Singapore 038982, Singapore; Institute of Biomedical Studies, Baylor University, Waco, TX 76712, USA. Electronic address: jeconnolly@imcb.a-star.edu.sg. ^[9]

关键词 EBV MDSC T cell immunotherapy nasopharyngeal carcinoma