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首页> Theranostics> Targeting BCL10 by small peptides for the treatment of B cell lymphoma.

Targeting BCL10 by small peptides for the treatment of B cell lymphoma.

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作者： Wei,Bao ^[1] ; Chenxia,Sun ^[2] ; Xiaochen,Sun ^[1] ; Miaoxia,He ^[2] ; Haolan,Yu ^[1] ; Wenfen,Yan ^[2] ; Fuping,Wen ^[3] ; Liang,Zhang ^[1] ; Chenghua,Yang ^[2]

作者单位： Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai, China, 200433. ^[1] CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China, 200031. ^[2] Department of Pathology, Changhai Hospital, Second Military Medical University, Shanghai, China, 200433. ^[3] Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, 1 Beichen West Road, Chaoyang District, Beijing, China, 100101. ^[4] Department of Plastic & Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, P.R. China. ^[5]

关键词 Bcl10 Bcl10 peptide inhibitors (BPIs)CARMA1-BCL10 supramolecular organizing centre (CB-SMOC)NF-κB diffuse large B-cell lymphoma (DLBCL)

主题词动物(Animals);抗肿瘤药(Antineoplastic Agents);细胞凋亡(Apoptosis);CARD信号接头蛋白质类(CARD Signaling Adaptor Proteins);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);女(雌)性(Female);鸟苷酸环化酶(Guanylate Cyclase);人类(Humans);淋巴瘤, 大B细胞, 弥漫性(Lymphoma, Large B-Cell, Diffuse);小鼠(Mice);显微镜检查, 电子(Microscopy, Electron);NF-κB(NF-kappa B);肽类(Peptides);蛋白质多聚化(Protein Multimerization);蛋白质稳定性(Protein Stability);信号传导(Signal Transduction);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)

DOI 10.7150/thno.47533

PMID 33052237

发布时间 2021-06-01

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Theranostics

Theranostics

2020年10卷25期

11622-11636页

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