Immune Profiling Enables Stratification of Patients With Active Tuberculosis Disease or Mycobacterium tuberculosis Infection.

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作者： Darragh,Duffy ^[1] ; Elisa,Nemes ^[2] ; Alba,Llibre ^[3] ; Vincent,Rouilly ^[1] ; Munyaradzi,Musvosvi ^[2] ; Nikaïa,Smith ^[4] ; Elizabeth,Filander ^[3] ; Hadn,Africa ^[1] ; Simbarashe,Mabwe ^[2] ; Lungisa,Jaxa ^[3] ; Bruno,Charbit ^[3] ; Humphrey,Mulenga ^[3] ; Michele,Tameris ^[3] ; Gerhard,Walzl ^[5] ; Stephanus,Malherbe ^[3] ; Stephanie,Thomas ^[3] ; Mark,Hatherill ^[6] ; Nicole,Bilek ^[6] ; Thomas J,Scriba ^[1] ; Matthew L,Albert ^[2] ; Milieu Intérieur Consortium ^[3]

作者单位： Immunobiology of Dendritic Cells, Institut Pasteur, Paris, France. ^[1] Inserm U1223, Institut Pasteur, Paris, France. ^[2] South African Tuberculosis Vaccine Initiative (SATVI), Division of Immunology, Department of Pathology and Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa. ^[3] DATACTIX, Paris, France. ^[4] Centre for Translational Research, Institut Pasteur, Paris, France. ^[5] Department of Science and Technology-National Research Foundation (DST-NRF) Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa. ^[6] Insitro, San Francisco, California, USA. ^[7]

关键词 biomarkers cytokines immune profiling patient stratification tuberculosis

主题词酶联免疫吸附测定(Enzyme-Linked Immunosorbent Assay);人类(Humans);干扰素γ(Interferon-gamma);潜伏性结核(Latent Tuberculosis);结核分枝杆菌(Mycobacterium tuberculosis);结核(Tuberculosis)

DOI 10.1093/cid/ciaa1562

PMID 33059361

发布时间 2021-11-10

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