Dysregulated RASGRP1 expression through RUNX1 mediated transcription promotes autoimmunity.

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第一作者： Matthijs J D,Baars

第一单位： Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

作者： Matthijs J D,Baars ^[1] ; Thera,Douma ^[2] ; Dimitre R,Simeonov ^[3] ; Darienne R,Myers ^[4] ; Kayla,Kulhanek ^[4] ; Saikat,Banerjee ^[5] ; Susan,Zwakenberg ^[5] ; Marijke P,Baltissen ^[5] ; Mojtaba,Amini ^[1] ; Sytze,de Roock ^[6] ; Femke,van Wijk ^[1] ; Michiel,Vermeulen ^[7] ; Alexander,Marson ^[2] ; Jeroen P,Roose ^[7] ; Yvonne,Vercoulen ^[6]

作者单位： Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands. ^[1] Center of Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands. ^[2] Diabetes Center, University of California San Francisco, San Francisco, CA, USA. ^[3] Biomedical Sciences Graduate Program, University of California San Francisco, San Francisco, CA, USA. ^[4] Department of Anatomy, University of California San Francisco, San Francisco, CA, USA. ^[5] Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, Nijmegen, The Netherlands. ^[6] Pediatric Immunology and Rheumatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands. ^[7] J. David Gladstone Institutes, San Francisco, CA, USA. ^[8] Department of Medicine, University of California, San Francisco, CA, USA. ^[9] Department of Microbiology and Immunology, University of California, San Francisco, CA, USA. ^[10]

关键词 RASGRP1 RUNX1 T cells autoimmunity transcription