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Specific Gene Co-variation Acts Better Than Number of Concomitant Altered Genes in Predicting EGFR-TKI Efficacy in Non-small-cell Lung Cancer.

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第一作者： Yan-Juan,Zhu

第一单位： Department of Oncology, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China; Department of Oncology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China.

作者： Yan-Juan,Zhu ^[1] ; Xin,Qu ^[1] ; Dan-Dan,Zhan ^[2] ; Hui-Hui,Chen ^[3] ; Hai-Peng,Li ^[4] ; Li-Rong,Liu ^[1] ; Xian,Chen ^[1] ; Yi-Hong,Liu ^[1] ; Yong,Li ^[1] ; Jian-Ping,Bai ^[1] ; Sheng,Ye ^[5] ; Hai-Bo,Zhang ^[6]

作者单位： Department of Oncology, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China; Department of Oncology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China. ^[1] Department of Oncology, The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China. ^[2] Department of Oncology, The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China; Department of Gynecology, Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine, Zhuhai, China. ^[3] Department of Oncology, The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China; Area 7 of Tumor Chemotherapy Department, Central Hospital of Guangdong Nongken, Zhanjiang, China. ^[4] Department of Oncology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. ^[5] Department of Oncology, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China; Department of Oncology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China; Guangdong Provincial Key Laboratory of Clinical Research on Traditional Chinese Medicine Syndrome, Guangzhou, China. Electronic address: haibozh@gzucm.edu.cn. ^[6]

关键词 Bio-marker Epidermal growth factor receptor tyrosine kinase inhibitors Next-generation sequencing Number of genetic variations Specific genetic alterations