Low-Dose LPS Induces Tolerogenic Treg Skewing in Asthma.

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作者： Fengxia,Ding ^[1] ; Bo,Liu ^[2] ; Chao,Niu ^[3] ; Ting,Wang ^[4] ; Yaping,Wang ^[2] ; Gang,Geng ^[5] ; Daiyin,Tian ^[1] ; Jihong,Dai ^[2] ; Zhou,Fu ^[3]

作者单位： Department of Pediatric Respiratory Medicine, Children's Hospital of Chongqing Medical University, Chongqing, China. ^[1] Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China. ^[2] China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing, China. ^[3] Chongqing Key Laboratory of Child Infection and Immunity, Chongqing, China. ^[4] Department of Cardiothoracic Surgery, Children's Hospital of Chongqing Medical University, Chongqing, China. ^[5]

关键词 GITRL LPS TLR4 asthma endotoxin tolerance

主题词动物(Animals);细胞凋亡(Apoptosis);哮喘(Asthma);树突细胞(Dendritic Cells);疾病模型, 动物(Disease Models, Animal);剂量效应关系, 免疫(Dose-Response Relationship, Immunologic);基因表达调控(Gene Expression Regulation);糖皮质激素类诱导TNFR相关蛋白质(Glucocorticoid-Induced TNFR-Related Protein);人类(Humans);免疫耐受(Immune Tolerance);脂多糖类(Lipopolysaccharides);淋巴细胞计数(Lymphocyte Count);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);卵白蛋白(Ovalbumin);信号传导(Signal Transduction);无特异性病原体有机物(Specific Pathogen-Free Organisms);T淋巴细胞, 调节性(T-Lymphocytes, Regulatory);Th17细胞(Th17 Cells);Th2细胞(Th2 Cells);Toll样受体4(Toll-Like Receptor 4);肿瘤坏死因子类(Tumor Necrosis Factors)

DOI 10.3389/fimmu.2020.02150

PMID 33072079

发布时间 2021-05-06

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Frontiers in immunology

2020年11卷

2150页

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Low-Dose LPS Induces Tolerogenic Treg Skewing in Asthma.

Frontiers in immunology

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Low-Dose LPS Induces Tolerogenic Treg Skewing in Asthma.

Frontiers in immunology

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Frontiers in immunology

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