Type-1 immunity and endogenous immune regulators predominate in the airway transcriptome during chronic lung allograft dysfunction.

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作者： Carlo J,Iasella ^[1] ; Aki,Hoji ^[2] ; Iulia,Popescu ^[2] ; Jianxin,Wei ^[2] ; Mark E,Snyder ^[2] ; Yingze,Zhang ^[2] ; Wei,Xu ^[2] ; Vera,Iouchmanov ^[2] ; Ritchie,Koshy ^[2] ; Mark,Brown ^[2] ; Monica,Fung ^[3] ; Charles,Langelier ^[3] ; Elizabeth A,Lendermon ^[2] ; Daniel,Dugger ^[3] ; Rupal,Shah ^[3] ; Joyce,Lee ^[3] ; Bruce,Johnson ^[2] ; Jeffrey,Golden ^[3] ; Lorriana E,Leard ^[3] ; Mary,Ellen Kleinhenz ^[3] ; Silpa,Kilaru ^[2] ; Steven R,Hays ^[3] ; Jonathan P,Singer ^[3] ; Pablo G,Sanchez ^[4] ; Matthew R,Morrell ^[2] ; Joseph M,Pilewski ^[2] ; John R,Greenland ^[3] ; Kong,Chen ^[2] ; John F,McDyer ^[2]

作者单位： Department of Pharmacy and Therapeutics, University of Pittsburgh School of Pharmacy, Pittsburgh, Pennsylvania. ^[1] Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania. ^[2] Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California San Francisco, San Francisco, California. ^[3] Department of Cardiothoracic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania. ^[4]

关键词 biomarker bronchiolitis obliterans (BOS)clinical research / practice immune regulation immunobiology lung (allograft) function / dysfunction lung transplantation / pulmonology molecular biology: mRNA / mRNA expression

主题词闭塞性细支气管炎(Bronchiolitis Obliterans);移植物排斥(Graft Rejection);人类(Humans);肺(Lung);肺移植(Lung Transplantation);蛋白质组学(Proteomics)

DOI 10.1111/ajt.16360

PMID 33078555

发布时间 2023-01-24

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