Quantitative Drug Dynamics Visualized by Alkyne-Tagged Plasmonic-Enhanced Raman Microscopy.

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作者： Kota,Koike ^[1] ; Kazuki,Bando ^[2] ; Jun,Ando ^[1] ; Hiroyuki,Yamakoshi ^[1] ; Naoki,Terayama ^[3] ; Kosuke,Dodo ^[4] ; Nicholas Isaac,Smith ^[4] ; Mikiko,Sodeoka ^[5] ; Katsumasa,Fujita ^[4]

作者单位： Department of Applied Physics, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan. ^[1] AIST-Osaka University Advanced Photonics and Biosensing Open Innovation Laboratory, National Institute of Advanced Industrial Science and Technology (AIST), 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan. ^[2] Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Aichi 467-8603, Japan. ^[3] Synthetic Organic Chemistry Laboratory, RIKEN Cluster for Pioneering Research, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan. ^[4] Immunology Frontier Research Center, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan. ^[5] Transdimensional Life Imaging Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan. ^[6]

关键词 Raman microscopy drug imaging gold nanoparticle small molecule surface-enhanced Raman scattering

主题词炔类(Alkynes);金(Gold);金属纳米粒子(Metal Nanoparticles);显微镜检查(Microscopy);药用制剂(Pharmaceutical Preparations);光谱分析, 拉曼(Spectrum Analysis, Raman)

DOI 10.1021/acsnano.0c05010

PMID 33079538

发布时间 2021-05-07

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