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Pairing a prognostic target with potential therapeutic strategy for head and neck cancer.

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第一作者： Sze Min,Lek

第一单位： Department of Sarcoma, Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, National Cancer Centre Singapore, 11 Hospital Crescent, Singapore 169610, Singapore.

作者： Sze Min,Lek ^[1] ; Ke,Li ^[1] ; Qiu Xuan,Tan ^[1] ; Nicholas B,Shannon ^[1] ; Wai Har,Ng ^[1] ; Josephine,Hendrikson ^[1] ; Joey W S,Tan ^[1] ; Hui Jun,Lim ^[1] ; Yudong,Chen ^[1] ; Kelvin K N,Koh ^[1] ; Thakshayeni,Skanthakumar ^[1] ; Xue Lin,Kwang ^[2] ; Fui Teen,Chong ^[2] ; Hui Sun,Leong ^[2] ; Gerald,Tay ^[3] ; Natascha Ekawati,Putri ^[1] ; Tony Kiat Hon,Lim ^[4] ; Jacqueline S G,Hwang ^[4] ; Mei Kim,Ang ^[5] ; Daniel S W,Tan ^[5] ; Ngian Chye,Tan ^[3] ; Hiang Khoon,Tan ^[3] ; Oi Lian,Kon ^[4] ; Khee Chee,Soo ^[3] ; N Gopalakrishna,Iyer ^[6] ; Chin-Ann J,Ong ^[7]

作者单位： Department of Sarcoma, Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, National Cancer Centre Singapore, 11 Hospital Crescent, Singapore 169610, Singapore. ^[1] Cancer Therapeutics Research Laboratory, National Cancer Centre Singapore, 11 Hospital Crescent, Singapore 169610, Singapore. ^[2] SingHealth Duke-NUS Head and Neck Centre, SingHealth, 1 Hospital Drive, Block 3 Basement 1, Singapore 169608, Singapore. ^[3] Department of Anatomical Pathology, Singapore General Hospital, 20 College Road, Singapore 169856, Singapore. ^[4] Division of Medical Oncology, National Cancer Centre Singapore, 11 Hospital Crescent, Singapore 169610, Singapore. ^[5] Cancer Therapeutics Research Laboratory, National Cancer Centre Singapore, 11 Hospital Crescent, Singapore 169610, Singapore; SingHealth Duke-NUS Head and Neck Centre, SingHealth, 1 Hospital Drive, Block 3 Basement 1, Singapore 169608, Singapore. Electronic address: gopaliyer@nccs.com.sg. ^[6] Department of Sarcoma, Peritoneal and Rare Tumours (SPRinT), Division of Surgery and Surgical Oncology, National Cancer Centre Singapore, 11 Hospital Crescent, Singapore 169610, Singapore; SingHealth Duke-NUS Oncology Academic Clinical Programme, SingHealth Duke-NUS Medical School, 8 College Rd, Singapore 169857, Singapore. Electronic address: johnny.ong.c.a@singhealth.com.sg. ^[7]

关键词 ATP13A3 protein Aurora A kinase Head and neck neoplasms Immunohistochemistry Molecular target therapy Squamous cell carcinoma of head and neck