<i>Ex Vivo</i> Gene Therapy Treats Bone Complications of Mucopolysaccharidosis Type II Mouse Models through Bone Remodeling Reactivation.

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第一作者： Miho,Wada

第一单位： Department of Pediatrics, The Jikei University School of Medicine, Tokyo, Japan.;Division of Gene Therapy, Research Center for Medicine Sciences, The Jikei University School of Medicine, Tokyo, Japan.

作者： Miho,Wada ^[1] ; Yohta,Shimada ^[2] ; Sayoko,Iizuka ^[2] ; Natsumi,Ishii ^[2] ; Hiromi,Hiraki ^[2] ; Toshiaki,Tachibana ^[3] ; Kazuhiro,Maeda ^[4] ; Mitsuru,Saito ^[4] ; Shoutaro,Arakawa ^[4] ; Takuya,Ishimoto ^[5] ; Takayoshi,Nakano ^[5] ; Hiroyuki,Ida ^[1] ; Toya,Ohashi ^[1] ; Hiroshi,Kobayashi ^[1]

作者单位： Department of Pediatrics, The Jikei University School of Medicine, Tokyo, Japan.;Division of Gene Therapy, Research Center for Medicine Sciences, The Jikei University School of Medicine, Tokyo, Japan. ^[1] Division of Gene Therapy, Research Center for Medicine Sciences, The Jikei University School of Medicine, Tokyo, Japan. ^[2] Division of Molecular Cell Biology, Research Center for Medical Science, The Jikei University School of Medicine, Tokyo, Japan. ^[3] Department of Orthopaedic Surgery, The Jikei University School of Medicine, Tokyo, Japan. ^[4] Biomaterials & Structural Materials Design Area, Course of Materials Science & Engineering, Division of Materials & Manufacturing Science, Graduate School of Engineering, Osaka University, Osaka, Japan. ^[5]

关键词 Hunter disease bone lineage bone mineral density bone strength ex?vivo gene therapy hematopoietic stem cell lentivirus mucopolysaccharidosis type II osteoblast osteoclast

DOI 10.1016/j.omtm.2020.09.012

PMID 33102618

发布时间 2024-08-02

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Molecular therapy. Methods & clinical development

2020年19卷

261-274页

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<i>Ex Vivo</i> Gene Therapy Treats Bone Complications of Mucopolysaccharidosis Type II Mouse Models through Bone Remodeling Reactivation.

Molecular therapy. Methods & clinical development

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Molecular therapy. Methods & clinical development

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<i>Ex Vivo</i> Gene Therapy Treats Bone Complications of Mucopolysaccharidosis Type II Mouse Models through Bone Remodeling Reactivation.

Molecular therapy. Methods & clinical development

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Molecular therapy. Methods & clinical development

相关期刊

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