Inhibition and induction of CYP enzymes in humans: an update.

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第一作者： Jukka,Hakkola

第一单位： Research Unit of Biomedicine, Pharmacology and Toxicology, University of Oulu, POB 5000, 90014, Oulu, Finland.;Biocenter Oulu, University of Oulu, Oulu, Finland.;Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, Finland.

作者： Jukka,Hakkola ^[1] ; Janne,Hukkanen ^[2] ; Miia,Turpeinen ^[3] ; Olavi,Pelkonen ^[4]

作者单位： Research Unit of Biomedicine, Pharmacology and Toxicology, University of Oulu, POB 5000, 90014, Oulu, Finland.;Biocenter Oulu, University of Oulu, Oulu, Finland.;Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, Finland. ^[1] Biocenter Oulu, University of Oulu, Oulu, Finland.;Research Unit of Internal Medicine, Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, Finland. ^[2] Research Unit of Biomedicine, Pharmacology and Toxicology, University of Oulu, POB 5000, 90014, Oulu, Finland.;Administration Center, Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, Finland. ^[3] Research Unit of Biomedicine, Pharmacology and Toxicology, University of Oulu, POB 5000, 90014, Oulu, Finland. olavi.pelkonen@oulu.fi. ^[4]

关键词 Cytochrome P450 Drug–drug interaction Environmental toxicants Herbal remedies Induction Inhibition