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Lysosomal Acid Lipase Is Required for Donor T Cells to Induce Graft-versus-Host Disease.

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第一作者： Hung D,Nguyen

第一单位： Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425, USA.

作者： Hung D,Nguyen ^[1] ; Taylor,Ticer ^[1] ; David,Bastian ^[1] ; Sandeepkumar,Kuril ^[2] ; Hong,Li ^[3] ; Hong,Du ^[4] ; Cong,Yan ^[4] ; Xue-Zhong,Yu ^[5]

作者单位： Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425, USA. ^[1] Department of Pediatric Hematology-Oncology, Medical University of South Carolina, Charleston SC 29425, USA. ^[2] Department of Public Health, Medical University of South Carolina, Charleston, SC 29425, USA. ^[3] Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indianapolis, IN 46202, USA. ^[4] Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425, USA; Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA. Electronic address: yux@musc.edu. ^[5]

关键词 GVHD GVL LAL T cells hematopoietic cell transplantation lipid metabolism orlistat

主题词移植物抗宿主病(Graft vs Host Disease);人类(Humans);固醇酯酶(Sterol Esterase);T淋巴细胞, 调节性(T-Lymphocytes, Regulatory)

DOI 10.1016/j.celrep.2020.108316

PMID 33113360

发布时间 2024-08-04

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